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Caspian Journal of Internal Medicine، جلد ۶، شماره ۳، صفحات ۱۷۷-۱۷۹
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عنوان انگلیسی Osteopoikilosis: a rare cause of bone pain
چکیده انگلیسی مقاله  Background: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. We present a case of 34-year-old man suffering from polyarthralgia and low back pain. Case presentation: A 34-year-old male patient, smoking 40 packs yearly and alcoholic was referred to our department of rheumatology, complaining of polyarthralgia which started 3 years ago and involving large and small joints. He reported the presence of pelvic pain mostly located at both hip joints and in the two ankles. On radiologic examination, numerous, symmetric, well defined, sclerotic lesions were identified on shoulder, wrist, ankles, pelvis, and on spine. The size of the lesions varied from 2 to 9 millimeters. These spots were located on spongious bone tissue, and in the inner bone cortex located bilaterally in the epiphyses and metaphyses. We concluded the diagnosis of OPK. His mother was found to have the same lesions without any symptoms. Conclusion: OPK may be an isolated finding or associated with other pathologies, e.g. skin manifestations, rheumatic and/or skeletal disorders. The main differential diagnosis is osteoblastic metastasis. 
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نویسندگان مقاله mahbouba jguirim | mahbouba jguirim
department of rhumatology , university of medicine of monastir, monastir, tunisia


mondher گلی | mondher golli
department of radiology monastir,university of medicine of monastir, monastir, tunisia


کاظمی پور mhenni | amira mhenni
department of rhumatology , university of medicine of monastir, monastir, tunisia


walid mnari | walid mnari
department of rhumatology , university of medicine of monastir, monastir, tunisia


naceur bergaoui | naceur bergaoui
department of rhumatology , university of medicine of monastir, monastir, tunisia
نشانی اینترنتی http://www.caspjim.com/browse.php?a_code=A-10-246-1&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Reumatology
نوع مقاله منتشر شده case report
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