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عنوان انگلیسی Parathyroid Adenoma and Hypercalcemic Crisis; a Rare Cause of Acute Pancreatitis
چکیده انگلیسی مقاله The relationship between primary hyperparathyroidism and pancreatitis has yet to be established firmly. We present a patient with acute pancreatitis and a hypercalcemic crisis induced by a parathyroid adenoma. A 72-year-old woman presented with lethargy and a constant pain in the epigastric region. She had a medical history of diabetes mellitus, hypertension, nephrolithiasis, and ischemic heart disease. Blood examination revealed leukocytosis and high serum amylase and lipase levels. Ultrasound exam confirmed the diagnosis of acute pancreatitis with a normal biliary tract and no gallstones. On further evaluation severe hypercalcemia (24 mg/dL) was detected, which was treated with 0.9% sodium chloride solution and calcitonin. The acute pancreatitis and its symptoms resolved after 3 days. Ultrasound exam and technetium 99m sestamibi scan showed a parathyroid lesion. Ultimately the patient underwent right thyroid lobectomy because of refractory hypercalcemia. The pathology report was indicative of a parathyroid adenoma. Subsequently, the parathyroid gland was resected with normalization of calcium, parathyroid hormone, and amylase levels and the patient was discharged in good condition 7 days after surgery. Apart from the acute supportive management, common to all cases of acute pancreatitis, definite management must be tailored to the specific cause. Hypercalcemia during the course of pancreatitis must prompt an investigation for primary hyperparathyroidism with early surgical intervention if a parathyroid source is detected.
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نویسندگان مقاله | Farid Poursadegh
Endocrinology department, Faculty of medicine, Mashhad University of medical sciences, Mashhad, Iran


| Parvin Layegh
Internal medicine department, Emamkhomeini hospital, Fariman, Iran


| Peyman Shalchian
Pathology resident, Faculty of medicine, Mashhad University of medical sciences, Mashhad, Iran


| Neda Bagherzadeh
Assistant professor of gasteroenterology and hepatology, Department of Gastroenterology and Hepatology, School of Medicine Mash¬had University of Medical Sciences, Mashhad, Iran


| Ladan Goshayeshi


نشانی اینترنتی http://govaresh.org/index.php/dd/article/view/1811
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/141/article-141-890853.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Report
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