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Middle East Journal of Cancer، جلد ۷، شماره ۲، صفحات ۸۵-۰
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عنوان انگلیسی The Debate on Pelvic Lymphadenopathy Size Significance in Ovarian Cancer Patients
چکیده انگلیسی مقاله Background: This study attempts to ascertain a reliable cutoff size to determine whether pelvic lymph nodes are metastatic or not in ovarian cancer patients. Methods: We retrospectively reviewed 73 PET/CT scans of 52 female patients with ovarian carcinoma who underwent surgery followed by chemotherapy. The findings of contrast enhanced MDCT were interpreted by two experienced radiologists unaware of the PET/CT findings. At least two experienced nuclear medicine physicians unaware of the contrast enhanced-MDCT findings examined the PET scans in order to localize, characterize and compare these scans to co-registered PET/CT images. A comparative study was done. Lymph node sizes were recorded in short axis diameter with a significant cut off estimated at 7.5 mm. Metabolic activities of different lymph node groups were assessed and the semi-quantitative SUV was calculated. The level of SUV significance was 2.5. Significant metastatic lymph nodes were judged by the assessment of integrated PET/CT results. Results: Of the 73 scans, 47 showed significant lymph node metastases, with the following sensitivities: 75% (external iliac), 77.8% (internal iliac), and 75% (inguinal). The specificities were 84% (external iliac), 86% (internal iliac), and 54% (inguinal) with a P-value of 0.000 for the external an internal iliac groups and 0.079 for the inguinal group. Conclusion: To improve detection of malignant pelvic lymph nodes, the size threshold should be decreased to 7.5 mm.
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نویسندگان مقاله همت a محمود | hemat a mahmoud
department of clinical oncology and nuclear medicine, assiut university hospital, assiut, egypt


haisam عطا | haisam atta
department of radiology, south egypt cancer institute, assiut university, assiut, egypt


waleed a diab | waleed a diab
department of clinical oncology and nuclear medicine, assiut university hospital, assiut, egypt


lamiaa m eloteify | lamiaa m eloteify
department of clinical oncology and nuclear medicine, assiut university hospital, assiut, egypt


عبد elmonem مراد | abd elmonem mourad
department of radiology, assiut university hospital, assiut, egypt


عادل gabr | adel gabr
department of medical oncology, south egypt cancer institute, assiut university, assiut, egypt


محمد a mekkawy | mohamed a mekkawy
department of clinical oncology and nuclear medicine, assiut university hospital, assiut, egypt


waleed m عمر | waleed m omar
department of nuclear medicine, national cancer institute, cairo university, cairo, egypt
نشانی اینترنتی http://mejc.sums.ac.ir/index.php/mejc/article/view/329
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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