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Middle East Journal of Cancer، جلد ۴، شماره ۱، صفحات ۳۵-۰
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عنوان انگلیسی Acute Acquired Demyelinating Polyneuropathy:An Initial Presentation of Diffuse Large B Cell Lymphoma
چکیده انگلیسی مقاله Neurological signs and symptoms are commonly associated with both Hodgkin’s and non-Hodgkin’s lymphoma and are mostly attributed to either direct lymphomatous involvement of the nervous system, either as a result of extension to the spinal cord or nerves, or due to infiltration by lymphoma cells and drug toxicity. Guillain-Barre syndrome and its variants have been reported very infrequently in the literature. We present the case of a 70-year-old male admitted to the hospital for evaluation of uncontrolled hypertension. Incidentally, he was noted to have a low platelet count and a leukoerythroblastic picture in the peripheral blood. Two days into admission, he developed bilateral symmetrical ascending paresis consistent with acute acquired demyelinating polyneuropathy, a common variant of Guillain-Barre syndrome. At about the same time he developed worsening cytopenia and was diagnosed with diffuse large B cell lymphoma according to a bone marrow biopsy. The patient was treated with intravenous immunoglobulin for Guillain-Barre syndrome with significant improvement in muscle strength and subsequently treated with chemotherapy for his lymphoma.
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نویسندگان مقاله munira shabbir moosajee | munira shabbir moosajee
aga khan university hospital, karachi, pakistan


غلام رحمانی mohyuddin | ghulam rehman mohyuddin
aga khan university hospital, karachi, pakistan


سارا خان | sara khan
aga khan university hospital, karachi, pakistan


ayeesha کامران کمال | ayeesha kamran kamal
aga khan university hospital, karachi, pakistan
نشانی اینترنتی http://mejc.sums.ac.ir/index.php/mejc/article/view/32
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Report
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