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Journal of Family and Reproductive Health، جلد ۹، شماره ۱، صفحات ۲۹-۳۳
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Effects of preoperative magnesium sulphate on post-cesarean pain, a placebo controlled double blind study.
چکیده انگلیسی مقاله To study the role of preoperative intravenous magnesium sulphate in decreasing post-cesarean pain and opioid requirement during first 24hrs.In a double blind randomized clinical trial, prior to induction of general anesthesia, fifty elective cesarean candidates were randomly assigned to one of the two groups of placebo or magnesium sulfate. After surgery visual analogue scale (VAS) and infused morphine by PCA during 24 hrs were recorded. The data were analyzed by mann-Whitney -test, analysis of variance, and student t- test.VAS was significantly lower among patients in the magnesium sulphate group at intervals of 1(st), 6(th) & 12(th) hours after cesarean section (C/S) with the mean scales of (48.9 ± 19.6 VS 74.7 ± 18.4), (42.1 ± 0.9 VS 58.3 ± 16.5) and (25.2 ± 6.1VS 30 ± 8.1) respectively and p-value of < 0.001, 0.002 and 0.05 respectively. However at 24 hrs there was no significant difference in VAS with mean VAS scales of 22.6 ± 4.5 VS 23.6 ± 4.9 and p-value of 0.49. The dose of infused Morphine during 24 hrs was significantly less in the magnesium sulphate group than the placebo group with the means of 4.36 ± 1.4 VS 7.02 ± 1.9 mg respectively (p < 0.001).Administration of bolus 50 mg/kg magnesium sulphate prior to induction of general anesthesia may significantly decreased the morphine requirement during immediate post operative period and can be recommended as one of the modalities of post-operative pain control in the pregnant patients.
کلیدواژه‌های انگلیسی مقاله Cesarean,General anesthesia,Magnesium sulfate,Opioid,Pain
نویسندگان مقاله سید محمد میراسکندری | seyed mohamad mireskandari
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

خلیل pestei | khalil pestei
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

اصغر حاجی پور | asghar hajipour
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

افشین جعفرزاده | afshin jafarzadeh
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شهرام صمدی | shahram samadi
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

امید نبویان | omid nabavian
department of anesthesiology, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jfrh.tums.ac.ir/index.php/jfrh/article/view/211
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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