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Journal of Family and Reproductive Health، جلد ۴، شماره ۳، صفحات ۹۵-۱۰۴
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عنوان انگلیسی Effects of Soy on Metabolic Biomarkers of Cardiovascular Disease in Elderly Women with the Metabolic Syndrome
چکیده انگلیسی مقاله Objective: To ascertain the effects of soy [in the forms of Textured Soy Protein (TSP) and soy-nut] on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers and blood pressure in elderly women with the metabolic syndrome. Materials and methods: The study is a 12-week parallel randomized controlled trial that was conducted in rural health centres of Babol, Iran. The participants were 75 women 60-70 years old with the metabolic syndrome who were randomized to one of the three groups of soy-nut (35g/d), TSP (35g/d) and control. Blood pressure and blood biochemical markers were measured at baseline and at the end of the study including, triglyceride, cholesterol, HDL-C, LDL-C, VLDL-C, ApoB100, ApoAI, CRP and fibrinogen. Results: The soy-nut improved significantly LDL-C, VLDL-C and Apo B100 (P< 0.05) while fewer improvements but significant were observed in these variables in the TSP group only when compared with the mean changes from the baseline (P< 0.001). Similar result was found for Apo AI in the treatment groups (P< 0.01). Serum total cholesterol decreased significantly in the treatment groups compared with control group (P< 0.005). The differences from control for triglyceride, HDL-C, fibrinogen, CRP and blood pressure were not significant. Conclusion: Both forms of soy while improved lipids profiles the soy-nut contribution was more to this improvement than the TSP. Therefore, moderate daily intake of soy may be a safe, cheap and practical method to improve cardiovascular disease risk and also reduce the need for medical treatment.
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نویسندگان مقاله افسانه بختیاری | afsaneh bakhtiary
institute of gerontology, university putra malaysia, serdang, selangor, malaysia. 2 department of mi


zaitun یاسین | zaitun yassin
1.institute of gerontology, university putra malaysia, serdang, selangor, malaysia. 3. department of


پریچهر حناچی | parichehr hanachi
faculty of basic science, department of biology, biochemistry unite, alzahra university tehran, iran

سازمان اصلی تایید شده: دانشگاه الزهرا (Alzahra university)

asmah رحمت | asmah rahmat
department of nutrition amp;amp; dietetics, faculty of medicine amp;amp; health sciences, university putra malaysi


zaiton احمد | zaiton ahmad
department of family medicine, faculty of medicine amp;amp; health sciences, university putra malaysia, ser


فرزاد جلالی | farzad jalali
department of cardiology, faculty of medicine, babol university of medical sciences, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

نشانی اینترنتی http://jfrh.tums.ac.ir/index.php/jfrh/article/view/98
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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