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Middle East Journal of Digestive Diseases، جلد ۹، شماره ۲، صفحات ۸۶-۹۳
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عنوان انگلیسی The Prevalence of Non-alcoholic Fatty Liver Disease and Diabetes Mellitus in an Iranian Population
چکیده انگلیسی مقاله BACKGROUND Type II diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) are important causes of morbidity and mortality worldwide. We aimed to estimate the prevalence of DM in the context of NAFLD. METHODS In this cross-sectional study, we studied 5052 participants, aged 18 years and older, of a baseline population-based cohort in northern Iran (N=6143). The prevalence of DM was estimated in individuals with and without NAFLD. The association between NAFLD and T2DM was evaluated using logistic regression with the adjustment of confounding effects of age, sex, body mass index, lipid profiles, and fasting insulin. RESULTS In men, the prevalence (95% confidence interval) of T2DM was 5.34% (4.35%-6.34%) and 15.06% (13.12%-17.00%) in individuals without and with NAFLD, respectively (p < 0.001). In women without NAFLD, the prevalence was 8.27% (6.83%-9.71%) while in the presence of NAFLD, the prevalence was 27.21% (24.59%-29.83%), (p < 0.001). In univariate analysis, the chance of having T2DM was 3.700 (3.130-4.380) times more in patients with NAFLD compared with subjects without NAFLD (p< 0.001). This chance was reduced (Odds Ratio=1.976, 95% CI: 1.593-2.451, p < 0.001) after removing the effects of other variables. CONCLUSION The prevalence of T2DM is increased in the context of NAFLD. This condition may be considered as an independent predictor of T2DM.
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نویسندگان مقاله | Behnam Rabiee


| Farzin Roozafzai


| Gholam Reza Hemasi


| Hossein Poustchi


| Hossein Keyvani


| Mahmood Reza Khonsari


| Hossein Ajdarkosh


| Mansooreh Maadi


| Fatemeh Sima Saeedian


| Farhad Zamani


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/1760
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/332/article-332-926894.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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