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Iranian Journal of Pathology، جلد ۱۱، شماره ۳، صفحات ۲۱۰-۲۱۵
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عنوان انگلیسی BK Viremia among Iranian Renal Transplant Candidates
چکیده انگلیسی مقاله Background: Primary infection with BK virus (BKV) is occurred during childhood and usually asymptomatic, but after initial infection, BKV may persist lifelong in the kidney and genitourinary tract. Reactivation may occur in individuals with compromised immunity such as renal transplant recipients. Due to the role of BKV in BK virus-associated nephropathy (BKVAN) and potentially renal allograft rejection, the detection of BKV in renal transplant candidates is very important. The aim of this study was to evaluate the frequency of BK viremia in end stage renal disease cases who were candidates for renal transplantation. Methods: In this cross-sectional study, 50 cases with end stage renal disease who were candidates for renal transplantation were recruited from the main dialysis unit in Tehran, Iran. Presence of BK viremia was determined in plasma samples of cases using real time PCR. Results: A total of 50 renal transplant candidates with mean age 37.8±13 yr were enrolled in the study. Fifty two percent of subjects were male. Forty six (92%) of them were under HD and 4 (8%) were on PD. BK virus was not detected in any plasma samples of renal transplant candidates. Conclusion: This study showed absence of BK viremia in our renal transplant candidates. However, due to the important role of BKV in BKVAN and renal graft failure and rejection, further studies involving larger number of cases are required to elucidate the rate of the BKV in renal transplant candidates. How to cite this article: Jozpanahi M, Ramezani A, Ossareh S, Banifazl M, Bavand A, Mamishi S, et al. BK Viremia among Iranian Renal Transplant Candidates. Iran J Pathol. 2016; 11(3):210-5.
کلیدواژه‌های انگلیسی مقاله BK virus (BKV),Prevalence,Renal transplant candidates
نویسندگان مقاله منیژه جزپناهی |
zanjan university of medical sciences, zanjan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (Zanjan university of medical sciences)

آمیتیس رمضانی |
clinical research dept., pasteur institute of iran, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (Zanjan university of medical sciences)

شهرزاد عصاره |
hasheminejad kidney center, iran university of medical science, tehran, iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

محمد بنی فضل |
iranian society for support of patients with infectious diseases, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

آناهیتا باوند |
clinical research dept., pasteur institute of iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

ستاره ممیشی |
pediatric infectious disease research center, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

آرزو آقاخانی |
clinical research dept., pasteur institute of iran, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijp.iranpath.org/article_19725_c6c8fe241477d519e1c3eab6d8aae293.pdf
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