این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pathology، جلد ۴، شماره ۴، صفحات ۱۷۲-۱۷۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Granulosa Cell – Stromal Tumors: An Immunohistochemical Study Including Comparison of Calretinin and Inhibin
چکیده انگلیسی مقاله Background and Objective: Histopathological evaluation of granulosa cell tumors (GCT) of the ovary may be confused morphologically with a wide variety of the tumors. Immunohistochemical staining for inhibin and calretinin can be used for better diagnosis. Although it has been suggested that inhibin can be a sensitive marker for GCT, it maybe had negative results in some cases. In addition, caltrinin has been proposed as a marker for GCT. The aim of this study was to investigate the immunohistochemical methods (IHC) including a comparison of calretinin and inhibin markers in the diagnosis of these tumors. Patients and Methods: This prospective study carried out from 2000 to 2009 at Ghaem and Omid hospitals, Mashad University of Medical Sciences, Iran. A total of 23 ovarian GCT specimens were immunostained with commercially available antibodies to find out calretinin and inhibin immunoreactivity. Data were analyzed by descriptive statistical method. A P value of =Results: For diagnosing GCT, the sensitivity of calretinin was 100% and that of the inhibin was almost 73.9%. The extent and severity of staining was more extensive for calretinin compared to inhibin PConclusion: Calretinin is a more sensitive biomarker for GCT than inhibin.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله زهره یوسفی |
dept. of obstetrics and gynecology, mashhad university of medical science.mashhad, iran

نوریه شریفی |
dept. of pathology, mashhad university of medical science, mashhad, iran

فرنوش سعادتمند |
dept. of obstetrics and gynecology, mashhad university of medical science.mashhad, iran

سودابه shaid ثالث | shaid salles
dept. of radiotherapy oncology, mashhad university of medical science, mashhad, iran

نشانی اینترنتی http://ijp.iranpath.org/article_8853_8d643e612ee129e6f6321056f7ea85a8.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات