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Iranian Journal of Pathology، جلد ۲، شماره ۴، صفحات ۱۴۴-۱۴۸
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عنوان انگلیسی Antimicrobial Susceptibility Pattern of Clinical Isolates of Pseudomonas Aeruginosa in a Pediatric Hospital
چکیده انگلیسی مقاله Background and Objective: Pseudomonas aeruginosa has become a frequent cause of nosocomial infections, particularly in intensive care units (ICUs). Many reports have documented high rates of resistance in this species to commonly-used broad-spectrum antibiotics. The aim of this study was to assess the in vitro activity of some antibiotics against Pseudomonas aeruginosa strains to determine the susceptibility patterns of isolates to different antibiotics. Materials and Methods: A total of 233 Pseudomonas aeruginosa isolates obtained from various clinical specimens of hospitalized children in Ali-Asghar hospital of Tehran (Iran) were considered for susceptibility test. These strains were tested against 12 different antibiotics by a disk diffusion method. Of these isolates, 33.9% were from trachea, 31.8% from urine, 6.9% from eye, 5.2% from blood, 5.1% from ear, 1.3% from cerebrospinal fluid, 1.2% from stool, and 14.6% from other sites. In addition, 48.5% of P. aeruginosa strains were isolated from patients in ICUs. Results: The most active antimicrobials were amikacin and other active compounds were gentamicin, ceftazidime, and ciprofloxacin respectively. Isolates from ICUs were more resistant to amikacin and gentamicin as compared to those from non-ICU wards (p
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نویسندگان مقاله سارا جمع |
iranian research center for hiv aids, tehran, iran

duman سبزواری |
iranian research center for hiv aids, tehran, iran

آرزو آقاخانی |
clinical research dept., pasteur institute of iran, tehran, iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

علی اسلامی فر |
clinical research dept., pasteur institute of iran, tehran, iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

محمد بنی فضل |
iranian society for support of patients with infectious diseases, tehran, iran

آمیتیس رمضانی |
clinical research dept., pasteur institute of iran, tehran, iran
سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

نشانی اینترنتی http://ijp.iranpath.org/article_8983_7893076daa27539696e1715f365f6609.pdf
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