این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pathology، جلد ۲، شماره ۳، صفحات ۱۰۹-۱۱۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Relationship between Pathologic and Laboratory Data of Children Suffering from Hemolytic Uremic Syndrome (HUS): A Center study
چکیده انگلیسی مقاله Background and objective: Hemolytic uremic syndrome (HUS) is the most prevalent cause of children renal insufficiency which in many cases (90%) occurs following diarrhea. Hemolytic microangiopathic anemia, thrombocytopenia, and renal insufficiency are main symptoms of hemolytic uremic syndrome. This study aims to consider the relationship between pathologic data of nephro-biopsy and laboratory data of children suffering from the disease. Material and Methods: This study has been carried out in retrospective, cross-sectional and descriptive procedures. For this purpose, 28 patients with an average age of 6 years suffering from uremic hemolytic syndrome referred to Ali Asghar Hospital over the last 10 years. Light microscopic data of glomeruli, arterioles, arteries, interstitial tissue, medullary vessels and tubules were evaluated. Laboratory data including hematology, biochemistry, and urinary tests were extracted from patients’ files. Data were analyzed using SPSS software. Results: The most prevalent damages in glomeruli were decreased capillary lumen and thickening of its wall and in arterioles were mild decrease of lumen and in artery thickening of intima and mild infiltration of inflammatory cells and mild edema in interstitial and hyperemia in vaso recta and the most prevalent pathology in tubules was the existence of cast. Significant relationship was found out between time of recovery of hematological disorders and medullary vessels congestion and reduplication of arterial inner elastic lamina and also improvement of biochemistry changes with glomerulus necrosis and leucocytes assembly in vaso recta. Arteriolar rate with creatinine serum level at discharge time was related and tubular rate with platelet count at discharging time was also related. Conclusion: Biopsy is an important tool for prognosis and det ermination of disease intensity. There was valuable statistical relationship between some laboratory data at the time of referral and pathological data which even could influence intensity or prognosis of disease.
کلیدواژه‌های انگلیسی مقاله Hemolytic Uremic Syndrome,histopathology,Laboratory
نویسندگان مقاله میترا mehrazama |
dept. of pathology, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

نکیسا هومن |
dept. of pediatric nephrology, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

علیرضا عبداللهی |
dept. of pathology, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسن اتوکش |
dept. of pathology, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijp.iranpath.org/article_8968_7c5d5dd6d633519ef56d0bdd57a66cb1.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات