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Iranian Journal of Pathology، جلد ۱، شماره ۳، صفحات ۹۱-۹۸
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عنوان انگلیسی Chromosomal Analysis Of Couples With Bad Obstetric Histoty
چکیده انگلیسی مقاله Background and Objective: Pregnancy termination and recurrent abortion are one of the common complications during pregnancy and in patients with a bad obstetric history. Materials and Methods: In this study, a total of 154 individuals including 75 couples four single women from different communities and with various incomes were investigated chromosomal abnormalities using blood culture and chromosomal banding technique. Results: Chromosomal analysis of these patients revealed three abnormal karyotypes (3.8%) in three women and two abnormal karyotypes in conceptions. Two of these couples had consanguineous marriage and the remaining women included one isochromosome for X [46, x,I (xq)], two translocations [45, xx, t (15:21)] and [46, xx, t (7:14)], one trisomy ‘21’ (47, xx, +21), and a ring chromosome (46, xx, r(X). In addition, 27 conceptions had been reported for these five couples. These included 23 abortions with 18 of them within first trimester (78.26%) and four of them had abortions within second trimester (21.74%), one had a normal child, three had abnormal children, and one with stillbirth. Conclusion: It was found out that abnormal karyotype is present in 3.8% of patients with a bad obstetric history. There was also a close relationship between number of deliveries and abortions and this relation was statistically significant (p
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نویسندگان مقاله علی محمد ملک عسگر | ali mohamad
genetic unit, deptartment of biochemistry, jondishapour university of medical sciences, ahvaz.

محمد اسماعیل مطلق | esmaeil motlagh
deptartment of pediatrics, jondishapour university of medical sciences, ahvaz.

محمود هاشمی تبار | hashemi tabar
deptartment of anatomy, jondishapour university of medical sciences, ahvaz

محمد علی غفاری | mohamad ali
deptartment of biochemistry, jondishapour university of medical sciences, ahvaz

نشانی اینترنتی http://ijp.iranpath.org/article_8910_c1549483ca7d121b06d9b262d514930d.pdf
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