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Basic and Clinical Neuroscience، جلد ۶، شماره ۴، صفحات ۲۹۹-۳۰۵
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عنوان انگلیسی Case Report: Combination Therapy with Mesenchymal Stem Cells and Granulocyte-Colony Stimulating Factor in a Case of Spinal Cord Injury
چکیده انگلیسی مقاله Introduction: Various neuroregenerative procedures have been recently employed along with neurorehabilitation programs to promote neurological function after Spinal Cord Injury (SCI), and recently most of them have focused on the acute stage of spinal cord injury. In this report, we present a case of acute SCI treated with neuroprotective treatments in conjunction with conventional rehabilitation program. Methods: A case of acute penetrative SCI (gunshot wound), 40 years old, was treated with intrathecal bone marrow derived stem cells and parenteral Granulocyte-Colony Stimulating Factor (G-CSF) along with rehabilitation program. The neurological outcomes as well as safety issues have been reported. Results: Assessment with American Spinal Injury Association (ASIA), showed neurological improvement, meanwhile he reported neuropathic pain, which was amenable to oral medication. Discussion: In the acute setting, combination therapy of G-CSF and intrathecal Mesenchymal Stem Cells (MSCs) was safe in our case as an adjunct to conventional rehabilitation programs. Further controlled studies are needed to find possible side effects, and establish net efficacy.
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نویسندگان مقاله نازی درخشان راد | nazi derakhshanrad
brain and spinal cord injury research center basir , imam khomeini hospital complex, keshavarz boulevard, tehran, iran


هوشنگ صابری | hooshang saberi
brain and spinal cord injury research center basir , imam khomeini hospital complex, keshavarz blvd., tehran, iran.


کیوان طیبی میبدی | keyvan tayebi meybodi
department of neurosurgery,imam khomeini hospital complex, keshavarz boulevard, tehran, iran.


محمد تقوایی | mohammad taghvaei
department of neurosurgery,imam khomeini hospital complex, keshavarz boulevard, tehran, iran


بابک ارجمند | babak arjmand
brain and spinal cord injury research center basir , imam khomeini hospital complex, keshavarz boulevard, tehran, iran


حمیدرضا آقایان | hamid reza aghayan
brain and spinal cord injury research center basir , imam khomeini hospital complex, keshavarz boulevard, tehran, iran


امیر حسن کهن | amir hassan kohan
brain and spinal cord injury research center basir , imam khomeini hospital complex, keshavarz boulevard, tehran, iran


محمد حق پناهی | mohammad haghpanahi
department of mechanical engineering, iran university of science and technology iust , tehran, iran

سازمان اصلی تایید شده: دانشگاه علم و صنعت ایران (Iran university of science and technology)

شاهرخ رحمانی | shahrokh rahmani
department of mechanical engineering, iran university of science and technology iust , tehran, iran

سازمان اصلی تایید شده: دانشگاه علم و صنعت ایران (Iran university of science and technology)

نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-114-1&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Cellular and molecular Neuroscience
نوع مقاله منتشر شده News and Reports
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