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Iranian Journal of Pediatric Hematology and Oncology، جلد ۵، شماره ۳، صفحات ۱۴۹-۱۵۴
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عنوان انگلیسی Serological Study on Cytomegalovirus and Toxoplasma Gondii in
چکیده انگلیسی مقاله Background Beta-thalassemia patients receive blood products from blood transfusion centers repeatedly. Blood transfusion can transmit Cytomegalovirus (CMV) and Toxoplasma gondii. The aim of this study was serological evaluation of these two infectious agents in thalassemia patients. Materials and Methods In a cross-sectional study, the enzymelinked immunosorbent assay (ELISA) testing was performed to detect IgM and IgG antibodies against CMV and Toxoplasma gondii in 96 thalassemia patients (under 18 years) and 144 healthy people. Data were analyzed by SPSS software and Chi-square test. Results A significant difference was observed in CMVIgM antibody levels between test group and control group in women (p< 0.05). The prevalence of CMV IgM, CMV IgG, Toxo-IgG, and Toxo IgM antibodies in thalassemia patients were 5.2%, 95.9%, 16%, and 0%, respectively. Conclusions: In all thalassemia patients, Cytomegalovirus IgG is higher than healthy people. In addition, CMV IgM antibodies are higher in female patients. Antibody screening (IgM) on blood products for detecting Cytomegalovirus is necessary, but for Toxoplasma gondii is not necessary in the Yazd transfusion center. Conclusion In all thalassemia patients, Cytomegalovirus IgG is higher than healthy people. In addition, CMV IgM antibodies are higher in female patients. Antibody screening (IgM) on blood products for detecting Cytomegalovirus is necessary, but for Toxoplasma gondii is not necessary in the Yazd transfusion center.
کلیدواژه‌های انگلیسی مقاله Beta-Thalassemia, Cytomegalovirus
نویسندگان مقاله m دوستی | m doosti
infectious and tropical diseases research center, shahid sadoughi university of medical sciences, yazd, iran


ha واحدیان اردکانی | ha vahedian ardakani
department of internal medicine, shahid sadoughi university of medical sciences, yazd, iran


a طالبی | a talebi
infectious and tropical diseases research center, shahid sadoughi university of medical sciences, yazd, iran.


m اخوان قالیباف | m akhavan ghalibaf
shahid sadoughi hospital, yazd, iran.


a نجفی | a najafi
department of clinical immunology, shahid sadoughi university of medical sciences, yazd, iran. shahid sadoughi hospital,


mm امین الرعایا | mm aminorroaya
shahid sadoughi hospital, yazd, iran


sh یزدانی | sh yazdani
department of virology, school of public health, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m شایسته پور | m shayestehpour
department of virology, school of public health, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m مقیمی | m moghimi
assistant professor of clinical and surgical pathology, department of pathology, shahid sadoughi ،yazd ،iran
نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-70-52&slc_lang=en&sid=en
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