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Iranian Journal of Pediatric Hematology and Oncology، جلد ۴، شماره ۲، صفحات ۵۷-۶۳
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عنوان انگلیسی Quality of life in patients with thalassemia major
چکیده انگلیسی مقاله Background With modern medical management, thalassemia major is now extending into adulthood and it is expected to have a negative impact on the quality of life (QOL) of the patients. The aim of this study was to evaluate quality of life in patients with thalassemia major. Materials and Methods This is an analytic case control study. Two hundred and fifty patients and 51 participants as controls were assessed using WHOQOL- BREF (Farsi version) questionnaire. All questions were answered based on the self-evaluated status in the past 2 weeks before enrollment and were rated on a five-point Likert scale. Therefore, the raw item score ranged from 1 to 5 and scaled in a positive direction and 6 dimensions including overall QOL, overall health, physical, psychological, social, and environmental relationship were assessed. Results Results showed that the QOL in all 6 dimensions was lower in patients compared to the controls (P< 0.05).Also age, higher education level, lower ferritin level and using oral iron chelator were associated with better QOL scores. On the other hand, cardiac disease, hepatitis C and history of psychiatric disorders were associated with impaired QOL scores. Conclusion These findings were important for future refinement of national thalassemia program. So, we recommended regular screening for psychiatric disorders and facilitated access to oral iron chelators. Regular monitoring and treatment of complications especially cardiac disease and hepatitis along with strict quality control of blood products were also mandatory. Also, higher education of the patients may improve quality of life.
کلیدواژه‌های انگلیسی مقاله Quality of life, Thalassemia Major, WHOQOLBREF
نویسندگان مقاله sh انصاری | sh ansari
pediatric hematologist- oncologist, department of the pediatric hematology and oncology, st ali- asqar hospital,tehran u


a باقرسلیمی | a baghersalimi
pediatric hematologist- oncologist, pediatrics growth disorders research center , 17 shahrivar hospital, school of medic


a آذرکیوان | a azarkeivan
pediatric hematologist- oncologist, iranian bloodtransfusion organization research center, tehran, iran.


m نجومی | m nojomi
professor of community medicine. department of community medicine, school of medicine, tehran university of medical scie

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

a حسن زاده راد | a hassanzadeh rad
pediatrics growth disorders research center, 17 shahrivar hospital, school of medicine, guilan university of medical sci

سازمان اصلی تایید شده: دانشگاه گیلان (Guilan university)

نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-70-12&slc_lang=en&sid=en
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