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Iranian Journal of Pediatric Hematology and Oncology، جلد ۳، شماره ۲، صفحات ۷۳-۷۷
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عنوان انگلیسی Effect of Thyroid Dysfunctions on Blood Cell Count and Red Blood Cell Indice
چکیده انگلیسی مقاله Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroidism on blood cell count and RBC indices. Materials and Methods This study performed on 102 patients with hypothyroid (14.1 years), 84 with hyperthyroid (15.6 years) and 118 healthy individuals (15.2 years) as control group. Initially patients TSH level of patients was determined by ELISA method, and then according to TSH ranges (0.3-5.5µIU/mL) patients were divided into two Hyperthyroidism (TSH< 0.3µIU/mL) and hypothyroidism (TSH>5.5µIU/mL) groups. Then, complete blood count was measured by cell counter. Finally, obtained results were analyzed by SPSS software. Results Analyzes of obtained data revealed statistically significant difference between two groups of patients in RBC count, MCH, MCHC, RDW, HB and HCT(P-value< 0.05), but the difference was not significant for WBC and PLT counts and MCV (P-value>0.05). Conclusion In case of patients with unknown hematological dysfunctions, must be evaluated for thyroid hormones.
کلیدواژه‌های انگلیسی مقاله Hypothyroidism, Hyperthyroidism, TSH
نویسندگان مقاله a درگلاله | a dorgalaleh


m محمودی | m mahmoodi


b ورمقانی | b varmaghani


f کیانی نوده | f kiani node


o سعیدی کیا | o saeeidi kia


sh علیزاده | sh alizadeh


sh طبیبیان | sh tabibian


t بامدی | t bamedi


m مومنی | m momeni


s عباسیان | s abbasian


نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1-78&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده پژوهشی
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