این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pediatric Hematology and Oncology، جلد ۲، شماره ۲، صفحات ۲۷-۷۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Anemia in Patients with Phenylketonuria in Yazd
چکیده انگلیسی مقاله Abstract Background Phenyl ketonuria (PKU) is a congenital metabolic disease. Irreversible brain damage is the result of phenyl alanin accumulation, so its amount should be restricted in patients diet. In their diet, trace elements such as hem Iron, folic acid, vitamin B12 and, etc are also limited, and could represent anemia. In this study, the frequency of anemia in PKU patients in Yazd was investigated and compare with non-affected individuals. Materials and Methods In this case-control study, all the PKU patients of Yazd who were under diet at least for 6 months were selected. The controls were selected from non PKU population and matched with cases according to age, gender and socioeconomic level. Hematologic factors were measured in both groups and analyzed using SPSS software using T-Test. Results This study consisted of 18 patients aged between 1 to 18 years old. Full blood count and blood indices did not show significant difference (p>0.05), except MCHC (p< 0.05). The blood level of vitamin B12 and Folic acid were significantly higher in the cases than controls (p< 0.05), but ferritin was not significantly different between them (P>0.05). Conclusion Our results did not show significant difference in presentation of anemia in patients with PKU and normal controls. Screening for anemia among PKU patients and taking supplements is recommended.
کلیدواژه‌های انگلیسی مقاله Phenyl ketonuria, Ferritins, Vitamin B12, Blood Cell Count
نویسندگان مقاله m اردویی | m ordooei
pediatric endocrinologist and professor assistant of pediatrics department of shahid sadoughi university of medical scie


g ملک زاده | g malekzadeh
medical student, shahid sadoughi university of medical sciences and health services, yazd, iran


a هاشمی | a hashemi
department of pediatric, hematology, oncology and genetic research center, shahid sadoughi university of medical science


m فرات یزدی | m forat yazdi
department of pediatric, hematology, oncology and genetic research center, shahid sadoughi university of medical science
نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1-87&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 1
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات