این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pediatric Hematology and Oncology، جلد ۱، شماره ۳، صفحات ۹۴-۹۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Relation between Left Ventricular Function and Serum Ferritin in Major Β-Thalassemia
چکیده انگلیسی مقاله Abstract Objective Cardiac dysfunction is a major cause of death in patients with beta thalassemia. In these patients, repeated blood transfusion, ineffective erythropoiesis and increased gastrointestinal iron absorption lead to iron overload in the body and this induced heart failure. Left ventricular ejection fraction was measured in major beta thalassemia (β-Th) patients to detect the relation of serum ferritin level and left ventricular systolic function. Materials and Methods The present prospective study evaluated 75 patients with β-thalassemia (39 female, 36 male) aged one to 44 years old. They were treated with desferal 5 days a week for at least six months. For this study they treated by desferal 7 days a week. Left ventricular ejection fraction and serum ferritin were measured before and after intervention, and they were compared for the best treatment. Results The mean ejection fraction was 60.45% and 62.9% before and after aggressive therapy, which difference was significant. Serum ferritin level also was reduced after intervention. Difference between mean ferritin before and after intervention was 49.984. Serum ferritin showed negative correlation with left ventricular function. Conclusion Lower serum ferritin concentration with aggressive therapy was associated with better left ventricular function.
کلیدواژه‌های انگلیسی مقاله β- thalassemia, ejection fraction, ferritin
نویسندگان مقاله سیما montazare لطف الهی | sima montazare lotfe elahi


اعظم سادات هاشمی | azam sadat hashemi
shahid sadoughi university of medical sciences and health services, yazd, iran


سید مصطفی بهجتی | seid mostafa behjati
department of pediatrics, hematology, oncology and genetics research center, shahid sadoughi university of medical scien


فریده zaolfaghari | farideh zaolfaghari
department of pediatrics, shahid sadoughi university of medical sciences and health services, yazd, iran


عاطفه دهقانی | atefeh dehghani
hematology, oncology and genetics research center, shahid sadoughi university of medical sciences and health services, y


مهوش اخوان قالیباف | mahvash akhavane ghalibaf
hematology, oncology and genetics research center, shahid sadoughi university of medical sciences and health services, y


محسن بیگمی | mohsen beigomi
- pediateric, shahid sadoughi university of medical sciences and health services, yazd, iran
نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-1-21&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 1
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات