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Journal of Research in Medical Sciences، جلد ۲۱، شماره ۳، صفحات ۰-۰
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عنوان انگلیسی Relationship between articular and nonarticular manifestations in inflammatory bowel diseases
چکیده انگلیسی مقاله Background: Musculoskeletal manifestations (MSM) of inflammatory bowel diseases (IBDs) are usually the most frequent extraintestinal manifestations. However, they are not paid enough attention during regular office visits. This cross-sectional study aimed to draw a clinical picture of MSM and their relationships with other findings in patients with IBD. Materials and Methods: Patients of our IBD cohort between March 2012 and September 2013 were consecutively evaluated. Those with current or past history of any MSM were examined by a rheumatologist. The outcome of interest was different MSMs. Distribution of IBD manifestations between the two groups of patients with ( n = 20) and without ( n = 253) MSM was compared. Logistic regression analysis was employed to find the relationships of demographic, clinical, and laboratory findings with MSM. Results: Two hundred and seventy-three patients were enrolled. Forty-two patients (15.4%) had extraintestinal manifestations of which twenty patients (7.5%) had at least one MSM. 7/20 patients (35%) versus 22/253 (8.7%) had other extraintestinal manifestations ( P = 0.0001). 12/20 patients (57%) had arthritis (polyarthritis, 33% and oligoarthritis, 67%). The most frequent involved joints were knee and ankle observed in 8 (40%) and 7 (35%) patients, respectively. The inflammatory back pain was recorded in 5/20 patients (25%) whereas two patients (10%) had ankylosing spondylitis. In regression analysis, oral aphthous (odds ratio [OR] =8.8 [95% confidence intervals (CI), 1.7–45], P = 0.009) and other extraintestinal manifestations (OR = 5.2 [95% CI, 1.3–20], P = 0.02) were significantly related with arthritis. Conclusion: The most frequent extraintestinal manifestations in patients with IBD were MSM. Knee and ankle were the most frequent involved joints. Extraintestinal manifestations were determinant variables of arthritis.
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نویسندگان مقاله علی محمد فاطمی | alimohammad fatemi


hourossadat هاشمی جزی | hourossadat hashemi jazi


محمد حسن امامی | mohammad hasan emami


امیر کاظمی زاده | amir kazemizadeh


حمید توکلی | hamid tavakkoli


عباس اسماعیلی | abbas smiley


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10448
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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