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Journal of Research in Medical Sciences، جلد ۱۹، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی Role of plasma ammonia level in detecting intra-abdominal hemorrhage following blunt abdominal trauma
چکیده انگلیسی مقاله Background: Blunt abdominal injury is a leading cause of death in trauma patients. A reliable test predicting intra-abdominal hemorrhage would be a novel method. The study objective was to assess the diagnostic accuracy of plasma ammonia in detection of intra-abdominal bleeding in patients with blunt abdominal trauma (BAT). Materials and Methods: In this observational study, all patients suffering from BAT, referred to our university teaching hospital included. The levels of ammonia were measured at the time of emergency department admission and 1 h after initial treatment. Demographic data, vital signs, and venous blood gas reports were recorded. Findings of contrast-enhanced abdominopelvic computed tomography scan and laparotomy were assumed as a gold standard for abdominal injuries. Results: A total of 104 patients was enrolled in the study. 15 patients (14.4%) had intra-abdominal hemorrhage and the mean plasma ammonia level in this group was significantly higher than the other patients on admission time (101.73 ± 5.41 ?g/dL vs. 47.36 ± 26.31 ?g/dL, P < 0.001). On receiver-operator characteristic curve analysis, in cutoff point of 89 ?g/dL, the sensitivity, specificity, positive and negative likelihood ratios were 100% (95% confidence interval [CI], 79.6-100), 93.26% (95%CI, 86-96.8), 14.83 (95% CI, 6.84-32.12), and 0, respectively. Conclusion: The study findings suggest the measurement of ammonia level at the time of admission in the patients with BAT would be a useful test predicting intra-abdominal hemorrhage. Furthermore,decrease in the ammonia level could be a useful marker for monitoring response to treatment in these patients.
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نویسندگان مقاله داود فارسی | davood farsi


علی اکبر خادمی فدکی | ali akbar khademi fadaki


ناهید کیان مهر | nahid kianmehr


سعید عباسی | saeed abbasi


مهدی رضایی | mahdi rezai


محمد مرعشی | mohammad marashi


مانی مفیدی | mani mofidi


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10097
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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