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Journal of Research in Medical Sciences، جلد ۱۹، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی Utility of serum creatinine/cystatin C ratio in diagnosis of postrenal acute kidney injury
چکیده انگلیسی مقاله Background: In obstructive uropathy, despite a severe increase in the serum creatinine (Cr) levels, only a mild cystatin C (CysC) increase was previously reported. Therefore, we aimed to determine the availability of serum Cr/CysC ratio in predicting postrenal acute kidney injury (AKI). Materials and Methods: This was a cross-sectional study involving 61-adult patients with heterogeneous AKI cases. Patients with bilateral pelvicalyceal dilatation in renal sonography were considered as postrenal AKI group ( n = 15) and others were intrinsic AKI group ( n = 46). Venous blood sampling for blood urea nitrogen, Cr and CysC measurements were performed on admission. Results: The mean age of study population was 66.3 ± 15.5 years; 38 (62%) of which were male. Two groups were similar regarding age, gender, and comorbidities. Cr/CysC ratio was significantly higher in postrenal AKI group (6.9 ± 3.1 vs. 4.4 ± 2.1, P =0.007). Conclusion: We suggest that serum Cr/CysC ratio seems to be a useful diagnostic tool for detection of postrenal AKI cases,especially for the cases without definite hydronephrosis.
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نویسندگان مقاله salih nal | salih nal


آتیلا altunta | atila altunta


veysel kidir | veysel kidir


alper özorak | alper özorak


یوسف lgin | yusuf lgin


مهمت tugrul sezer | mehmet tugrul sezer


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10096
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Short Communications
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