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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی Scolicidal effects of Squash (Corylus spp) seeds, Hazel (Curcurbia spp) nut and Garlic (Allium sativum) extracts on hydatid cyst protoscolices
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Background: Because there is no effective drug therapy for hydatid cyst yet, assessment and finding of some new agents especially from herbal origin with a desired scolicidal effect attracts great attention for treatment and pre-surgical use to prevent the hydatid cyst recurrence. Hazelnut, squash seeds and garlic chloroformic and hydro-alcoholic extracts’ scolicidal effects were examined. Materials and Methods: Suspension of protoscolices was obtained from infected liver and or lung of sheep and goats from Ziyaran abattoir. The chloroformic and hydro-alcoholic extracts from hazelnut, squash seeds and garlic were extracted using the succilate method. Scolicidal effect of each extract assessed in different concentrations and effected time using microscopy and 0.1% eosin solution stained only killed protoscolices. Results: Present study showed that garlic had more potent scolicidal effects among all the 3 plants and the chloroformic extract of garlic was the most potent protoscolicid among all of the extracts and killed 98% of protoscolices in 50 mg/ml on a minimum of 20 minutes of exposure. Conclusion: Garlic chloroformic extract is a safe and potent protoscolicid and might be used in hydatid cyst treatment and pre-surgery to prevent secondary cyst recurrence.
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نویسندگان مقاله عباس علی اسکندریان | abbas ali eskandarian
department of parasitology amp;amp;mycology,faculty of medicine,isfahan university of medical sciences,isfahan,iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8738
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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