| چکیده انگلیسی مقاله |
BACKGROUND: The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology . METHODS: A total of 94 patients who had indication of endoscopy entered the study. All of the 5 tests were performed for each patient . When the results of at least 2 tests were positive (except serology), Helicobacter pylori infection was considered to be positive . The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under receiver operating characteristic (ROC) curve of these 5 tests were determined . RESULTS: The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under ROC curve of these 5 tests are as below, respectively. Histology: 89 % , 78 % , 93 % , 91 % , 85 % and 0 . 881; RUT: 93 % , 75 % , 95 % , 94 % , 86 % and 0 . 831; serology: 50 % , 54 % , 46 % , 61 % , 52 % and 0 . 563; stool antigen test: 96 % , 83 % , 98 % , 96 % , 91 % and 0 . 897; UBT: 89 % , 73 % , 92 % , 90 % , 82 % and 0 . 892. CONCLUSIONS: Stool antigen test is the most accurate test for Helicobacter pylori diagnosis before eradication of these bacteria . KEYWORDS: Helicobacter Pylori, Stool Antigen Test, Urea Breath Test. BACKGROUND: The purpose of this study is to compare validity of 5 diagnostic tests of helicobacter pylori with each other: stool antigen test, urea breath test (UBT), rapid urease test (RUT), serology and histology. METHODS: A total of 94 patients who had indication of endoscopy entered the study. All of the 5 tests were performed for each patient. When the results of at least 2 tests were positive (except serology), Helicobacter pylori infection was considered to be positive. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under receiver operating characteristic (ROC) curve of these 5 tests were determined. RESULTS: The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and area under ROC curve of these 5 tests are as below, respectively. Histology: 89%, 78%, 93%, 91%, 85% and 0.881; RUT: 93%, 75%, 95%, 94%, 86% and 0.831; serology: 50%, 54%, 46%, 61%, 52% and 0.563; stool antigen test: 96%, 83%, 98%, 96%, 91% and 0.897; UBT: 89%, 73%, 92%, 90%, 82% and 0.892. CONCLUSIONS: Stool antigen test is the most accurate test for Helicobacter pylori diagnosis before eradication of these bacteria. KEYWORDS: Helicobacter Pylori, Stool Antigen Test, Urea Breath Test. |
| نویسندگان مقاله |
شادی کاظمی | shadi kazemi
resident, department of internal medicine, school of medicine and student research committee isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
حمید توکلی | hamid tavakkoli
associate professor, department of internal medicine, school of medicine, isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
محمد رضا حبیب زاده | mohamad reza habibzadeh
anesthesiologist, amin hospital, isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
محمد حسن امامی | mohammad hassan emami
associate professor, department of internal medicine, school of medicine, isfahan university of medical sciences, isfahan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
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