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Journal of Research in Medical Sciences، جلد ۱۱، شماره ۵، صفحات ۳۱۳-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of D-penicillamine in prevention of post operative pelvic adhesion formation in rat
چکیده انگلیسی مقاله INTRODUCTION: Adhesion formation after pelvic surgery is still a major cause of several morbidities such as infertility, pain, bowel obstruction and subsequent intra-operative complications. Our aim was to investigate the effects of d-penicillamine in preventing adhesion formation in rat uterine horn. METHODS: This experimental trial was conducted on 30 rats. The rats were randomly assigned to two groups of 15. Measurable serosal injury was created using a standard technique. The rats in one of the two groups were given 17 mg/kg of d-penicillamine. All of the animals were operated on 4 weeks after surgery and adhesions were assessed and scored by an examiner who was blind to the test. RESULTS: Frequency of severe adhesions in control and case groups were 76 and zero percent, respectively. Total scores of adhesions were found to be significantly reduced in the d-penicillamine treatment group when compared with control group (P = 0). CONCLUSION: This study showed that penicillamine can decrease the chance of post-operative intra-peritoneal adhesion formation. KEY WORDS: Adhesion formation, d-penicillamine, pelvis.
کلیدواژه‌های انگلیسی مقاله Key words, Adhesion formation, d-penicillamine, pelvis.
نویسندگان مقاله عطا الله قهیری | ata allah ghahiri
department of gynecology and obstetrics, isfahan university of medical science

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

الهه زارعان | elahe zarean
department of gynecology and obstetrics, isfahan university of medical science

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

مهدی راستی | mehdi rasti
department of surgery, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

شهریار ادیبی | shahriar adibi
research center, school of dentistry, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/205
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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