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Avicenna Journal of Phytomedicine، جلد ۵، شماره ۵، صفحات ۴۲۷-۴۳۳
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عنوان انگلیسی Saffron supplements modulate serum pro-oxidant-antioxidant balance in patients with metabolic syndrome: A randomized, placebo-controlled clinical trial
چکیده انگلیسی مقاله Objectives: We have investigated the effect of a saffron supplement, given at a dose of 100 mg/kg, on prooxidant-antioxidant balance (PAB) in individuals with metabolic syndrome. Materials and Methods: A randomized, placebo-controlled trial design was used in 75 subjects with metabolic syndrome who were randomly allocated to one of two study groups: (1) the case group received 100mg/kg saffron and (2) the placebo control group received placebo for 12 weeks. The serum PAB assay was applied to all subjects before (week 0) and after (weeks 6 and 12) the intervention. Results: There was a significant (p=0.035) reduction in serum PAB between week 0 to week 6 and also from week 0 to week 12. Conclusion: Saffron supplements can modulate serum PAB in subjects with metabolic syndrome, implying an improvement in some aspects of oxidative stress or antioxidant protection.
کلیدواژه‌های انگلیسی مقاله metabolic syndrome, Prooxidant-antioxidant Balance, saffron
نویسندگان مقاله طیبه کرمانی | tayyebeh kermani
department of anatomy and cell biology, birjand university of medical sciences, birjand, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

سید هادی موسوی | seyyed hadi mousavi
pharmacological research center of medicinal plant, faculty of medicine, mashhad university of medical science, mashhad, iran.


مریم shemshian | maryam shemshian
biochemistry of nutrition research center, school of medicine, mashhad university of medical science, mashhad, iran.


عبدالرضا نوروزی | abdolreza norouzy
biochemistry of nutrition research center, school of medicine, mashhad university of medical science, mashhad, iran.


محسن مزیدی | mohsen mazidi
institute of genetics and developmental biology, university of chinese academy of sciences, beijing, china.


عاطفه معزی | atefeh moezzi
biochemistry of nutrition research center, school of medicine, mashhad university of medical science, mashhad, iran.


تکتم مقیمان | toktam moghiman
biochemistry of nutrition research center, school of medicine, mashhad university of medical science, mashhad, iran.


مجید غیور مبرهن | majid ghayour mobarhan
cardiovascular research center, faculty of medicine, mashhad university of medical science, mashhad, iran.


گوردون a ferns | gordon a ferns
division of medical education, brighton amp;amp; sussex medical school, rm 342, mayfield house, university of brighton, bn1 9ph, united kingdom
نشانی اینترنتی http://ajp.mums.ac.ir/article_4672.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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