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Medical Journal of Islamic Republic of Iran، جلد ۱۴، شماره ۳، صفحات ۲۴۱-۲۴۳
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عنوان انگلیسی NEOADJUVANT CHEMOTHERAPY WITH VINCRISTINE AND CISPLATIN FOLLOWED BY RADICAL HYSTERECTOMY AND PELVIC LYMPH ADENECTOMY FOR FIGO STAGE IB BULKY CERVICAL CANCER
چکیده انگلیسی مقاله Twenty patients with bulky (>4 cm size) FIGO stage IB cervical cancer were treated with cisplatin 50 mg/m2 and vincristine 1 mg/m2, administered intravenously at 10-day intervals for a total of 3 courses before radical hysterectomy. A complete clinical response was noted in 1 patient (5%) and partial response in 5 (25%). Fourteen patients (70%) had stable disease. There was no grade 3 toxicity noted. Of the 20 patients who received chemotherapy (ChT), 3 patients had parametrial and para-aortic involvement in these cases, the operation was aborted and radiation therapy given. The remaining 17 patients underwent radical hysterectomy and pelvic lymphadenectomy 10-15 days following ChT. Five of these patients (29.4%) had pelvic node metastases. Three patients had positive margins. These 8 patients received postoperative radiotherapy. Twenty-four months later 15 patients were alive (87%) and 2 had died.
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نویسندگان مقاله n بهتاش | n behtash
from the department of gynecology-oncology, vali-e-asr hospital, tehran university 0f medical sciences, tehran, i.r. iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

m مدرس | m modares
from the department of gynecology-oncology, vali-e-asr hospital, tehran university 0f medical sciences, tehran, i.r. ira

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

f قایم مقامی | f ghaem maghami
from the department of gynecology-oncology, vali-e-asr hospital, tehran university 0f medical sciences, tehran, i.r. ira

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

a موسوی | a mousavi
from the department of gynecology-oncology, vali-e-asr hospital, tehran university 0f medical sciences, tehran, i.r. ira

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

k صالحی | k salehi
from the department of gynecology-oncology, vali-e-asr hospital, tehran university 0f medical sciences, tehran, i.r. ira

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-314&slc_lang=en&sid=en
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