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International Journal of Pediatrics، جلد ۴، شماره ۵، صفحات ۱۶۹۷-۱۷۰۳
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عنوان انگلیسی Adverse Events Following Immunization (AEFI) in Children under 7- year of Age during 2014 in Hamedan Province, Iran
چکیده انگلیسی مقاله Background: The surveillance of adverse events following immunization (AEFI) is essential to improve high standard of vaccine safety, and maintain public trust in immunization programs. This study aimed to determine the AEFI and their related factors in children. Materials and Methods: This cross-sectional study including all children under 7- year of age, in Hamadan Province, the West of Iran, in 2014. All of the AEFI related with Bacille Calmette-Guérin (BCG), Diphtheria, Pertussis, and Tetanus (DPT), Measles, Mumps, and Rubella (MMR) vaccines were obtained from the documented record-based by Health Centers, in Hamadan province. Results: From a total of 239,204 doses administered, 284 AEFI were notified (11.8 per 10,000 doses). The proportion of AEFI was more frequently reported from Health Houses than Health Centers (60.2 vs. 37.0, P< 0.05). The most frequently AEFI reported was lymphadenitis (31.4%), followed by hyperpyrexia (17%), and severe local reaction (13.5%). Most frequently AEFI reported were related to vaccination reaction (74.7%) and programmatic errors (12.7%). Also, for incidence of lymphadenitis, the overall median time from vaccination to adverse event was 2 days (IQR: 2-15) and the highest median time was 15 days (IQR: 15-571). Conclusion: Our study shown, an increased risk of AEFI in the region and point out that the programmatic error still needs to be considered. Accordingly, the more activities need to be consolidated to reduce the adverse effect. This study assessed the different aspects of AEFI which may help policymakers to improve the immunization programs.
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نویسندگان مقاله سلمان خزایی | salman khazaei
department of epidemiology amp;amp; biostatistics, school of public health, hamadan university of medical sciences, hamadan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

شهاب رضاییان | shahab rezaeian
social development amp;amp; health promotion research center, gonabad university of medical sciences, gonabad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

محسن رازانی | mohsen razani
faculty member of nursing department, broujerd branch, islamic azad university, broujerd, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

علی ظهیری | ali zahiri
expert of public health, deputy of health, hamadan university of medical sciences, hamadan, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

محمد ساعتچی | mohamad saatchi
department of epidemiology amp;amp; biostatistics, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

سمیه خزایی | somayeh khazaei
expert of operating room, rafsanjan university of medical sciences, rafsanjan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

عبداله محمدیان هفشجانی | abollah mohamadian hafshjani
social determinants in health promotion research center, hormozgan university of medical sciences, bandar abbas, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی رفسنجان (Rafsanjan university of medical sciences)

مهفام درویشی | mahfam darvishi
lorestan university of medical sciences, khorramabad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی هرمزگان (Hormozgan university of medical sciences)

نشانی اینترنتی http://ijp.mums.ac.ir/article_6705.html
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