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International Journal of Pediatrics، جلد ۳، شماره ۵.۲، صفحات ۹۸۷-۹۹۴
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عنوان انگلیسی Effect of Vitamin D supplementation on Lipid Profile in Children Aged 10-14 Years Old
چکیده انگلیسی مقاله Introduction Considering the high prevalence of vitamin D deficiency in our country and the importance of blood lipid profile as a protective factor, aim of this study was to investigate the effect of vitamin D supplementation on lipid profile in children 10 to 14 years.Materials and Methods In this controlled clinical trial study, 40 children who were studying on 2014 in Birjand elementary schools were selected and randomly divided into two groups containing 20 participants. Children in both group examined for level of lipid profile and serum vitamin D after and before consumption of drugs (vitamin D supplement and placebo). Questionnaire was used in order to record demographic information. Data was analyzed using SPSS-16 statistical software and statistical tests of Chi-square, Fisher exact test, t-paired, independent-t, and Pearson correlation at significance level of P< 0.05.Results The results showed that in children of intervention group the average of High-density lipoprotein (HDL) serum level and vitamin D was significantly higher after intervention before it (P< 0.05); the average of Low-density lipoprotein (LDL) serum level was significantly increased (P< 0.05), but there was no significant difference in LDL/HDL ratio, cholesterol and Triglyceride before and after intervention. In control group there was no significant difference between the average of vitamin D and blood lipid profile before and after intervention. Conclusion According to the results of this study there is a significant increase in HDL and LDL after using vitamin D supplement, and suggested more studies with larger sample sizes to be done in this area.
کلیدواژه‌های انگلیسی مقاله Children, Lipid profile, vitamin D
نویسندگان مقاله کوکب نمکین | kokab namakin
department of pediatric, school of medicince, birjand university of medical sciences, birjand, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

فاطمه توکلی | fatemeh tavakoli
pediatric rezident, department of pediatric, school of medicince, birjand university of medical sciences, birjand, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

محمود زردست | mahmoud zardast
department of pathology, school of medicince, birjand university of medical sciences, birjand, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

نشانی اینترنتی http://ijp.mums.ac.ir/article_5141.html
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