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Medical Journal of Islamic Republic of Iran، جلد ۱۳، شماره ۳، صفحات ۱۸۵-۱۸۹
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عنوان انگلیسی RENAL ALLOGRAFT ACCUMULATION OF TECHNETIUM-99M SULFUR COLLOID AS A PREDICTOR OF GRAFT REJECTION
چکیده انگلیسی مقاله A perplexing issue in diagnosing the cause of renal allograft dysfunction is differentiation between rejection----the most common cause--and many other possibilities that have detrimental effects on graft function. This study was designed to determine whether technetium - 99m sulfur colloid (TSC) accumulation could predict graft rejection. We prospectively studied 54 episodes of allograft dysfunction in 53 kidney transplant recipients who had undergone TSC scintiscanning and graft biopsy, within one week of evidence of allograft dysfunction. Visual analysis of TSC uptake was done by comparing allograft uptake with that of the fifth lumbar vertebra (L5) marrow. A 3+ result meant that allograft uptake was greater than L5 marrow uptake 2+, allograft uptake was the same as L5 marrow uptake 1+, less than and 0, no allograft uptake. Transplant accumulation of 􀁀2+ was considered consistent with rejection (p=0.01). Allotransplant biopsies were interpreted based on the Banff Working Classification and rejection was noted in 45 of 54 renal biopsies. 42 of 45 biopsy -proven rejection episodes had ≥2+ graft uptake. This nuclear medicine technique has a sensitivity of 93.3%, specificity of 44.4%, a positive predictive value of 89.3%, a negative value of 57.1 % and an efficiency of 83.3% in the diagnosis of renal allograft rejection.
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نویسندگان مقاله بهزاد عین اللهی | behzad einollahi
from the department of nephrology, baghiyatollah hospital, baghiyatollah university of medical sciences


محمدرضا خاتمی | mohammadreza khatami
the department of nephrology, imam khomeini hospital, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محبوب لسان پزشکی | mahboob lesanpezeshki
the department of nephrology, imam khomeini hospital, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

پژمان بختیاری | pejman bakhtiari
from the department of nephrology, baghiyatollah hospital, baghiyatollah university of medical sciences


ویولت امیرجلالی | violet amirjalali
the department of nuclear medicine, shahid labafinejad hospital, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

احمد فیروزان | ahmad firouzan
the department of nephrology, azad islami university of medical sciences, tehran, i. r. iran.
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-387&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Nephrology
نوع مقاله منتشر شده Original Research
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