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Medical Journal of Islamic Republic of Iran، جلد ۱۲، شماره ۳، صفحات ۲۳۵-۲۳۹
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چکیده فارسی مقاله
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عنوان انگلیسی EVALU ATION OF INSULIN-SUL FONYLUREA COMBINATION V ERSIJS INSULIN AL ONE IN THE T REATMENT OF NON-INSULIN D EPENDENT DIABETES MELLITU S (NID DM)
چکیده انگلیسی مقاله Lowering the glucose level in diabetic patients reduces the risk of many consequences which are usually reported in these patients. Non-insulin dependent (type II) diabetes which cannot be controlled with sulfonylureas alone can be controlled with a combination of sulfonylurea and insulin. In an open randomized trial 58 patients were divided into three groups. The fIrst group received only insulin based on their blood glucose level. The second group received a set amount of insulin plus the required amount of glibenclamide and the third group received a set amount of insulin plus the required amount of chlorpropamide based on their glycemic control. All three groups had a significant reduction of blood glucose, total cholesterol and triglyceride levels. The best long term glycemic control was in the second group with the lowest HbAlc(% ). In these patients bedtime insulin and daytime sulfonylurea (B IDS) gives better glycemic control. This method of therapy is a valuable option for patients with NIDDM whose hyperglycemia cannot be controlled by sulfonylureas and do not have compliance with more than one injection a day.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله k غلامی | k gholami
from the department of clinical pharmacy, college of pharmacy, tehran university of medical sciences,tehran, and the department of endocrinology, college of medicine, tehran university of medical sciences, tehran, i.r. iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m پژوهی | m pajoohi


a مالمیر | a malmir


n جزایری | n jazayeri


نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-452&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pharmacology
نوع مقاله منتشر شده Original Research
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