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The Journal of Tehran University Heart Center، جلد ۱۴، شماره ۲، صفحات ۴۷-۵۲
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عنوان انگلیسی In-Hospital Outcome of Patients with Diabetes Mellitus after CTO Recanalization with Third-Generation Drug-Eluting Stents
چکیده انگلیسی مقاله Background: Percutaneous coronary intervention (PCI) of total chronic coronary occlusions (CTOs) still remains a major challenge in interventional cardiology. There is little knowledge in the literature about differences in CTO-PCI between diabetic and nondiabetic patients in the era of third-generation drug-eluting stents (DESs). In this study, we analyzed the impact of diabetes mellitus (DM) on procedural characteristics, complications, and acute outcomes in a cohort of 440 patients. Methods: Between 2012 and 2016, we recruited 440 consecutive patients, 116 of them with DM. All the patients underwent PCI for at least 1 CTO. Antegrade and retrograde CTO recanalization techniques were applied. Only third-generation DESs were used. We used t-tests and the Pearson chi-quadrat test to test the significant differences in the variables between the 2 groups. Results: The patients with DM were older than the nondiabetics (64.5 y vs. 61.1 y; P=0.003), and they suffered more frequently from a chronic kidney disease (7.1% vs. 2.4%; P=0.001). The nondiabetics less frequently had arterial hypertension (75.3% vs. 89.7%; P=0.001); however, they more often had a family liability for CAD (32.1% vs. 22.4%; P=0.050) and had a higher left ventricular  ejection fraction (59.2% vs. 56.7%; P=0.011). The success rate was 85.2% in the patients without DM and 81.2% in the patients with DM (P=0.403). The existence of DM had no impact on the procedural success and complication rates. Conclusion: Our study on 440 patients shows that diabetics and nondiabetics have similar success and complication rates after the recanalization of CTOs using third-generation DESs. It is a feasible and safe procedure and can be recommended as an alternative treatment.
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نویسندگان مقاله | Jan Guelker
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.


| Lars Bansemir
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.


| Rainer Ott
Institute for Heart and Circulation Research, University Cologne, Cologne, Germany.


| Thomas Rock
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.


| Rosemarie Guelker
RWI Leibniz Institute for Economic Research, Essen, Germany.


| Dong-In Shin
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.


| Heinrich Klues
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.


| Alexander Bufe
Heartcentre Niederrhein, Department of Cardiology, Helios Clinic Krefeld, Krefeld, Germany.
نشانی اینترنتی http://jthc.tums.ac.ir/index.php/jthc/article/view/637
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