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Medical Journal of Islamic Republic of Iran، جلد ۱۰، شماره ۲، صفحات ۱۱۷-۱۲۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی THE EFFECTS OF DEPRESSION ON ENDOICRINE AND IMMUNE SYSTEMS
چکیده انگلیسی مقاله To study the effect of depression on the endocrine and immune systems, 557 male freshman and sophomore medical students (20-30 years old) were given Beck's Depression Inventory. Students with marks 5 or above were selected as the control (n=26) and those with marks of 20 or higher were chosen as the test group (n=27). All of the students were subjected to the following tests: CBC, differential, total cholesterol (TC), triglycerides (TG), HDL-c, VLDL-c, fibrinogen (Fibr), cortisol (Cort), prolactin (PRL), testosterone(Test), triiodothyronine (T3), thyroxine (T4), total serum immunoglobulins (Ig), IgA, IgG, IgM, creatine kinase (CK), and C3 and C4 components of the complement system. Results indicated statistically significant increases of the following parameters in the test group as compared with the controls: TC (P < 0.05), LDL-c (P < 0.05), CK (P < 0.025), Fibr (P < 0.0 1), Test (P < 0.05), Cort (P < 0.025), IgG (P < 0.025) and Ig (P < 0.025). The results were in accordance with the anticipated hormonal and cell-mediated immunity alterations caused by depression, which affected both cytokines and endorphin levels. In spite of the limited number of subjects used in this study and lack of the dexamethasone suppression test (DST), the overall approach of this study is encouraging nevertheless, further studies using a 1zrger sample are required.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله mh قهرمانی | mh ghahramani
from the schools of paramedical sciences , shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

m نظری | m nazari
from the schools of paramedical sciences , shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

sz تابعی | sz tabei
from the schools of medicine, shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

j احمدی | j ahmadi
from the schools of medicine, shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

sn رفعتی | sn rafati
from the schools of paramedical sciences , shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

ma قلمبر | ma ghalambor
school of paramedical sciences, shiraz university of medical sciences, shiraz, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-443&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده General
نوع مقاله منتشر شده Original Research
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