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Iranian Journal of Chemistry and Chemical Engineering، جلد ۳۷، شماره ۴، صفحات ۱۰۱-۱۱۵
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عنوان انگلیسی Pseudo-Five-Component Condensation for the Diversity-Oriented Synthesis of Novel Indoles and Quinolines Containing Pseudo-Peptides (Tricarboxamides)
چکیده انگلیسی مقاله A novel series of indole and quinoline tricarboxamides were synthesized using simple and efficient one-pot pseudo-five-component reactions of 2-formylindole or 2-chloro-3-formyl quinolines, isocyanides, amines, and Meldrum's acid as a CH-acid in CH2Cl2 at room temperature. This conversion has been achieved via the construction of new bonds including two C-C bonds, two C-N bonds, and one C=O bond. Remarkably, three peptide bonds were formed through a domino sequence including Knoevenagel reaction, [1+4] cycloaddition, deacetonation and also, aminolysis reaction. Particularly, a number of structurally remarkable and pharmacologically significant products were provided in excellent yields.
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نویسندگان مقاله Morteza Shiri |
Department of Chemistry, Faculty of Science, Alzahra University, Tehran, I.R. IRAN

Majid M. Heravi |
Department of Chemistry, Faculty of Science, Alzahra University, Tehran, I.R. IRAN

Vahideh Zadsirjan |
Department of Chemistry, Faculty of Science, Alzahra University, Tehran, I.R. IRAN

Atefeh Nejatinezhad-Arani |
Department of Chemistry, Faculty of Science, Alzahra University, Tehran, I.R. IRAN

Suhas Ashok Shintre |
School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X54001, Durban, 4000, SOUTH AFRICA

Neil Anthony Koorbanally |
School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X54001, Durban, 4000, SOUTH AFRICA

نشانی اینترنتی http://www.ijcce.ac.ir/article_28213_fe78afbfbacb0eb77ccffc182226c60b.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/444/article-444-1477078.pdf
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