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Medical Journal of Islamic Republic of Iran، جلد ۹، شماره ۲، صفحات ۱۳۱-۱۳۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A STUDY OF FREE RADICAL INJURY TO VITAL ORGANS
چکیده انگلیسی مقاله The study of toxicities which are caused by free radical inducing chemicals (e.g., carbon tetrachloride), helps to determine the mode of action of those important drugs which act by inhibiting free radicals. Evaluation of toxicities induced by carbon tetrachloride and phenobarbitone administration was carried out in seventy healthy male rabbits. Each animal received CCI4 0.25-0.5 mL/kg body weight, intraperitoneally, twice weekly for eleven doses. During this period, the only water which was provided for drinking to these animals contained 0.25 g/L pentobarbitone. Examination of these animals revealed that carbon tetrachloride produced severe liver and kidney injuries which could be assessed by physical parameters, liver and kidney function tests, and microscopic .examinations of the vital organs of these aninlals.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله عفت زهرا | iffat zehra
from the department of pharmacology, faculty of pharmacy, university of karachi


محمد طارق آفتاب | mohammad tariq aftab
from the department of pharmacology, faculty of pharmacy, university of karachi


asif بین رحمانی | asif bin rehman
from the department of pharmacology, faculty of pharmacy, university of karachi


قمر جمال | qamar jamal
the department of pathology, institute of basic medical sciences, jinnah post graduate medical center, karachi, pakistan.


شهید رشید | shahid rashid
from the department of pharmacology, faculty of pharmacy, university of karachi
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-543&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pharmacology
نوع مقاله منتشر شده Original Research: Basic Science in Medicine
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