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Iranian Journal of Parasitology، جلد ۱۴، شماره ۲، صفحات ۳۳۴-۳۳۹
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عنوان انگلیسی Detection of Chilomastix mesnili in Common Marmoset (Callithrix jacchus) and Treatment with Metronidazole
چکیده انگلیسی مقاله Background: Recently, the use of common marmoset (Callithrix jacchus) has increased in biomedical research as an animal model. This study aimed to test fecal samples to monitor bacterial and parasite infections in common marmoset at the Laboratory Animal Center of Osong Medical Innovation Foundation in Korea. Methods: To monitor bacteria and parasites in common marmoset, we tested 43 fecal samples of 43 common marmosets by culture and parasitological test in 2014. Infection by Chilomastix mesnili was determined by PCR method. Results: We identified nonpathogenic bacteria such as Proteus mirabilis and Escherichia coli in feces of normal common marmosets. Interestingly, C. mesnili was isolated from a healthy common marmoset by fecal centrifugation concentration and PCR. The monkey infected with C. mesnili was treated with metronidazole. After the treatment, C. mesnili were not found in feces using fecal centrifugation concentration and PCR. Conclusion: This is the first case report of C. mesnili infection in common marmoset. Treatment with metronidazole is found to be highly effective in eradicating C. mesnili infection in common marmoset.
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نویسندگان مقاله | Eui-Suk JEONG
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Repub-lic of Korea Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea


| Jong-Hyung PARK
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Repub-lic of Korea


| Seung-Hyun RYU
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Repub-lic of Korea


| Soo-Young CHOI
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Repub-lic of Korea


| Kyoung-Sun LEE
Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea


| Jong-Man KIM
Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea


| Byung-Hwa HYUN
Laboratory Animal Center, Osong Medical Innovation Foundation, Chungbuk 28160, Republic of Korea


| Yang-Kyu CHOI
Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Repub-lic of Korea
نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/2061
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