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Medical Journal of Islamic Republic of Iran، جلد ۶، شماره ۲، صفحات ۱۴۳-۱۴۵
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عنوان انگلیسی THE EFFECT OF ALUMINUM ON BIOCHEMICAL PARAMETERS RELATED TO BONE METABOLISM. A MODEL STUDY OF HEMODIALYSIS PATIENTS
چکیده انگلیسی مقاله The influence of aluminum on some serum parameters related to bone metabolism has been investigated by daily administration of aluminum over different periods of time. Daily administration of aluminum (1 mg/kg BW) for 20 or 50 days elevated serum phosphorous concentration by 16 percent and had no significant effect on serum calcium level. When aluminum was injected as a complex with citric acid (1 :1) there was a 22 percent elevation in serum phosphorous concentration, but again had no significant effect on serum calcium. Same amounts of aluminum caused a 28 percent elevation in serum alkaline phosphatase (ALKP), but had no significant effect on serum parathormone (PTH) either with or without citric acid. A marked reduction (about 41 percent) in serum calcitonin was observed when rats were given aluminum with or without citric acid. The relationship between aluminum toxicity and osteomalacia has been discussed.
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نویسندگان مقاله aa مشتاقی | aa moshtaghie
from the dept. of biochemistry, school of pharmacy, isfahan university of medical sciences, isfahan, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

| a sobhani
from the department of pharamacology, faculty of medicine, gilan universily of medical sciences, rasht
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-698&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pharmacology
نوع مقاله منتشر شده Original Research: Basic Science in Medicine
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