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Medical Journal of Islamic Republic of Iran، جلد ۶، شماره ۲، صفحات ۱۳۵-۱۳۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A STUDY OF THE INTRACELLULAR KILLING OF THE PERIPHERAL BLOOD NEUTROPHILS IN β- THALASSEMIA MAJOR PATIENTS
چکیده انگلیسی مقاله 52 β- thalassemia major patients were studied. Their ages ranged from two to 20 years. The group consisted of 22 girls and 30 boys. Candida intracellular killing and NBT (nitroblue tetrazolium) tests were performed on the peripheral blood neutrophils of these patients. Average results of the intracellular killing test was within normal range for the patients, but showed an appreciable decrease in comparison with the results of the normal control tests (50 normal persons of the same age group were tested as normal controls. This decrease was more pronounced in those patients who had undergone splenectomy. A converse relationship was observed between the results of the patients' intracellular killing and their serum ferritin level and age. Average results of the patients' NBT tests showed an increase in comparison with those of the control group. The average results for the patients who had their spleens removed due to hypersplenism was the same as in those who had normal spleens and had no relation to the serum ferritin level but did show a moderate relationship with the age of the patients. A suggestion that can be put forth is the likelihood that intracellular killing of peripheral blood neutrophils in the β- thalassemia patients is conductive to the determination of those with greater susceptibility to infection.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمد جعفری | mohammad jaafari
from the amp;apos; tarbiat modarres university tehran, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

مینا ایزدیار | mina izadyar
children amp;apos;s medical center, tehran university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد رخشان | mohammad rakhshan
dept. of pathology, shaheed beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

ابوالحسن farhoudc | abul hassan farhoudc
children amp;apos;s medical center, tehran university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

طاهره زندیه | tahereh zandieh
blood transfusion organization, tehran, islamic republic of iran.

سازمان اصلی تایید شده: سازمان انتقال خون ایران (Blood transfusion research center)

غلامرضا بابک | gholam reza babal
from the amp;apos; tarbiat modarres university tehran, islamic republic of iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-696&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Blood
نوع مقاله منتشر شده Original Research: Basic Science in Medicine
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