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Medical Journal of Islamic Republic of Iran، جلد ۲۹، شماره ۱، صفحات ۹۹۲-۱۰۰۰
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عنوان انگلیسی Relationship between esophageal clinical symptoms and manometry findings in patients with esophageal motility disorders: a cross-sectional study
چکیده انگلیسی مقاله Background: Manometry is the gold-standard diagnostic test for motility disorders in the esophagus. The development of high-resolution manometry catheters and software displays of manometry recordings in color-coded pressure plots have changed the diagnostic assessment of esophageal disease. The diagnostic value of particular esophageal clinical symptoms among patients suspected of esophageal motor disorders (EMDs) is still unknown. The aim of this study was to explore the sensitivity, specificity, and predictive accuracy of presenting esophageal symptoms between abnormal and normal esophageal manometry findings. Methods: We conducted a cross-sectional study of 623 patients aged 11-80 years. Data were collected from clinical examinations as well as patient questionnaires. The sensitivity, specificity, and accuracy were calculated after high-resolution manometry plots were reviewed according to the most recent Chicago Criteria. Results: The clinical symptoms were not sensitive enough to discriminate between EMDs. Nevertheless, dysphagia, noncardiac chest pain, hoarseness, vomiting, and weight loss had high specificity and high accuracy to distinguish EMDs from normal findings. Regurgitation and heartburn did not have good accuracy for the diagnosis of EMDs. Conclusion: Clinical symptoms are not reliable enough to discriminate between EMDs. Clinical symptoms can, however, discriminate between normal findings and EMDs, especially achalasia.
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نویسندگان مقاله هاشم فخر یاسری | hashem fakhre yaseri
internist , gastroenterologist, research center for gastroenterology and liver disease, department of internal medicine and gastroenterology, firoozgar hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Research Center for Gastroenterology and Liver Disease

علی محمد فخر یاسری | ali mohammad fakhre yaseri
school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علی برادران مقدم | ali baradaran moghaddam
department of microbiology, school of medicine, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

سید کامران سلطانی arabshhi | seyed kamran soltani arabshhi
internist, department of internal medicine, firoozgar hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Firoozgar Hospital

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-896&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
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