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Iranian Journal of Medical Sciences، جلد ۴۴، شماره ۶، صفحات ۵۱۱-۵۱۴
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عنوان انگلیسی Acantholytic and Pagetoid Variant of Bowen’s Disease with Microinvasion on the Scalp of a Young Female Patient: A Case Report
چکیده انگلیسی مقاله Bowen’s disease (BD) is a non-melanoma skin cancer with several histological subtypes. Herein we describe a case of a 35-year-old woman with a 4-cm diameter crusted plaque on the parietal scalp region. She had the lesion for 2 years. It had previously been histologically diagnosed as pemphigus vulgaris and only treated with a topical cream. The lesion progressively became thicker and larger. A new biopsy showed atypical cell proliferation through the whole thickness of the epidermis and follicular epithelium, with dermal microinvasion along with acantholysis and clear cell formation. The patient underwent total lesion excision (1 cm margin) with the diagnosis of both acantholytic and pagetoid subtypes of BD and dermal microinvasion. We describe a rare case of a young female patient with both subtypes of BD present in one lesion on an area not exposed to the sunlight. The lesion was initially misdiagnosed as pemphigus vulgaris.
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نویسندگان مقاله Maryam Nasimi |
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Arghavan Azizpour |
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Azita Nikoo |
Department of Pathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Robabeh Abedini |
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran

Safoura Shakoei |
Department of Dermatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

نشانی اینترنتی http://ijms.sums.ac.ir/article_45771_89efd149e5e3efb2be49d4fbd371587c.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/147/article-147-2060653.pdf
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