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Medical Journal of Islamic Republic of Iran، جلد ۳۴، شماره ۱، صفحات ۲۸-۳۲
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عنوان انگلیسی Prevalence and antibiotic resistance of Acinetobacter baumannii among patients in postcardiac surgery intensive care units of Rajaei Hospital, Tehran
چکیده انگلیسی مقاله Background: Acinetobacter baumannii is an opportunistic, aerobic, nonfermentative, Gram-negative bacterium that can cause major nosocomial infections, especially in patients hospitalized in intensive care units (ICU). Recently, A. baumannii strains have been resistant to a variety of antibiotics. Thus, it was aimed to evaluate the prevalence of A. baumannii and their resistance to the antibiotics in the patients hospitalized in postcardiac surgery ICU.    Methods: This retrospective cross sectional study was performed in Rajaei hospital between March 2014 and February 2016. A. baumannii strains were isolated from blood cultures, catheter cultures, sputum cultures, and wound smear cultures. Then, isolates were characterized using standard morphological, cultural, and biochemical properties according to CLSI 2016. The frequency of A. baumannii species were reported as percent.    Results: Among 27 167 patients were admitted to the ICU, 113 individuals, including 55 males and 58 females, were identified as A. baumannii-infected and the prevalence rate was 0.42%. The highest rates of antibiotic sensitivity were related to Meropenem 20 (17.7%) and Colistin 16 (14.1%). The shortest length of stay (LOS) for patients with A. baumannii in the ICU was 3 days, while the longest LOS was 98 days.    Conclusion: The findings indicated that A. baumannii strains isolated from postcardiac surgery ICUs had a high prevalence and were sensitive to Meropenem and Colistin. However, new molecular-based techniques are needed to monitor nosocomial infections. Therefore, the treatment of the patients may be feasible by appropriate antibiotic therapy, and infection control policies will be improved by adopting precise disinfection strategies.
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نویسندگان مقاله | Monireh Kamali
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran


| Shirin Manshouri
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran


| Yasser Bagheri
Immunology Research Center, Institute of Immunology and infectious Diseases, & Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Masoumeh Rostami
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran


مهدی کارخانه محمودی | Mahdi Karkhaneh Mahmoudi
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran


پردیس مرادنژاد | Pardis Moradnezhad
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran


| Farhad Seif
Neuroscience Research Center, Iran University of Medical Sciences, & Academic Center for Education, Culture, and Research, Tehran, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-5153-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/18/article-18-2318165.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Disease
نوع مقاله منتشر شده Original Research
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