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International Journal of Pediatrics، جلد ۸، شماره ۵، صفحات ۱۱۳۳۱-۱۱۳۴۰
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عنوان انگلیسی Comparison of Intelligence Quotient in Early Treated Neonates with Congenital Hypothyroidism Compared to Healthy Children
چکیده انگلیسی مقاله Background: Congenital hypothyroidism (CH) is one of the preventable causes of intellectual disability. The aim of this study was to compare intelligence quotient (IQ) in early treated children with CH and healthy children. Materials and Methods: This cohort study was conducted on 78 early treated children with CH (patient group) identified in screening program in Qazvin, Iran, started in 2006 and 90 age and sex matched healthy children (control group). The Persian version of Wechsler scale was performed to assess IQ (full scale, verbal, performance). Full-scale score among 70 and 80 were defined as borderline IQ and score among 50 and 69 were defined as mild mental retardation. Data were analyzed using SPSS software version 16.0. Results: Mean age was 6.57±1.92 in patients group and 6.94±1.57 in control group (P>0.05). 46/78 of the patient group and 51/90 of the control group were male (P>0.05). Mean full scale (87.01±13.47 vs. 107.45±10.49; P< 0.001), verbal (85.73±13.54 vs. 106.86±10.18; P< 0.001), and performance (89.44±13.66 vs. 110.62±9.82; P< 0.001) IQ in the patients group were significantly lower than the control group. 73.1% of the patients group had average and above IQ. Borderline IQ (14.1% vs. 0) and mild mental retardation (12.8% vs. 1.1%, P
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نویسندگان مقاله | Banafsheh Arad
Assisstant Professor of Pediatric Nephrology, Children Growth Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran, Qazvin, Iran.


| Neda Esmailzadehha
PhD Student of Epidemiology, Student Research Committee, School of Health, Iran University of Medical Sciences, Tehran, Iran.


| Ali Homaei
Student of Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Farzaneh Rohani
Associate Professor of Pediatric Endocrinology, Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Science, Tehran, Iran.


| Fatemeh Saffari
Associate Professor of Pediatric Endocrinology, Children Growth Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
نشانی اینترنتی http://ijp.mums.ac.ir/article_14300.html
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