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Medical Journal of Islamic Republic of Iran، جلد ۲۹، شماره ۱، صفحات ۳۸۵-۳۹۱
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عنوان انگلیسی Serum levels of vitamins A and D, and zinc in children with acute diarrhea: A cross-sectional study
چکیده انگلیسی مقاله Background: Diarrhea is a leading cause of mortality and morbidity during the early life period especially in developing countries. Micronutrients deficiencies have been proposed either as a risk factor or a consequence of diarrhea. Association studies highlight the relation of vitamins and minerals’ deficiencies with acute diarrhea. In this regard we aimed to evaluate the status of vitamins A and D, and zinc serum levels in children with acute diarrhea. Methods : In this cross sectional study performed in a referral teaching hospital, we measured and compared baseline vitamin A, 25-hydroxy vitamin D (25(OH)D), and zinc serum levels in 25 children admitted with acute diarrhea and 25 other children who were admitted for undergoing elective surgeries. Results : 25-(OH)D levels were significantly lower in the diarrhea group (p=0.03). We were unable to demonstrate a significant difference in the levels of vitamin A and zinc between the case and control groups (p= 0.14 and p=0.07, respectively). Conclusion : We observed lower serum 25(OH)D levels in children with acute diarrhea. Whether this finding indicates a premorbid risk factor or simply a consequence of diarrhea needs further studies. Regardless of the cause and effect relationship, supplementation with vitamin D in acute diarrhea remains as a plausibleconsideration.
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نویسندگان مقاله الهام طلاچیان | elham talachian
pediatric gastroenterology division ali-asghar children’s hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

علی بیداری | ali bidari
emergency department, hazrat-e-rasoulakram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

ثمیله نوربخش | samileh noorbakhsh
department of pediatric infectious diseases, hazrat-e-rasoulakram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

آذردخت طباطبایی | azardokht tabatabaei
pediatric infectious disease research center, hazrat-e-rasoulakram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

فرشته سالاری | fereshteh salari

سازمان های دیگر: Pediatric Specialist

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-827&slc_lang=en&sid=en
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