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Medical Journal of Islamic Republic of Iran، جلد ۳۶، شماره ۱، صفحات ۲۸۳-۲۸۷
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چکیده فارسی مقاله
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عنوان انگلیسی Estimating the Prevalence of Bladder Cancer by Stage in Iran as a Developing Country
چکیده انگلیسی مقاله Background: Bladder cancer is among the 10 most common cancers globally and in Iran. The prevalence rate is a crucial metric for both estimating disease burden and policymakers. On the other hand, bladder cancer is a heterogeneous disease with different stages, high recurrence, and progression rate. In planning treatment procedures, it is important to know the prevalence of bladder cancer by stages. In the current study, we aimed to estimate the 5-year prevalence of bladder cancer by stages using the Markov model.     Methods: This was a simulation study. To estimate the 5-year prevalence of bladder cancer by stages, we used the Markov model with a time horizon of 5 years following diagnosis. We simulated the natural history of bladder cancer using a literature review. We extracted survival rate, stage-specific recurrence, and progression rate using local and international publications and expert opinion. In addition, we used the Iranian life table and extracted probabilities of mortality due to other causes of death.    Results: Five-year prevalence of bladder cancer for the year 2018 was estimated at 21,807 patients. Non- muscle-invasive bladder cancer accounted for around 68% of all cases, with 42% in the Ta low-grade stage. About 32% of bladder cancer prevalent cases were muscle-invasive bladder cancer patients, from which about 8% had metastatic tumors.      Conclusion: Researchers and policymakers can utilize the findings of this study to conduct economic burden analyses and plan resource allocation.
کلیدواژه‌های انگلیسی مقاله Markov Model, Bladder Cancer, Prevalence, Stage, Epidemiology, Iran
نویسندگان مقاله | Hamideh Rashidian
Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran


| Ali Akbar Haghdoost
Regional Knowledge Hub, and WHO Collaborating Centre for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran


| Rajabali Daroudi
Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Mehdi Raadabadi
Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Mohammad Reza Ebadzadeh
Department of Urology, Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran


| Kazem Zendehdel
Cancer Research Center, & Cancer Biology Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7104-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Biostatistics and Epidemiology
نوع مقاله منتشر شده Original Research
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