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Medical Journal of Islamic Republic of Iran، جلد ۳۶، شماره ۱، صفحات ۲۴۹-۲۵۳
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عنوان انگلیسی Effective High Grade Cervical Intraepithelial Neoplasia Case Finding in Low Resource Settings
چکیده انگلیسی مقاله Background: Visual Inspection with Acetic Acid (VIA) is an inexpensive option for cervical cancer screening.  In this study, we evaluated the role of the VIA as well as of the clinical symptoms/signs to find the best case-finding method for Cervical Intraepithelial Neoplasia (CIN) 2+.    Methods: In a cross-sectional study, we extracted from records the demographic characteristics, clinical symptoms/signs, and indications for colposcopy referral of patients with CIN 2+ in pathology. Patients were divided into 1- Abnormal Pap smear, 2- Positive VIA, 3- abnormal Pap smear with clinical symptoms/signs, 4-VIA positive with clinical symptoms/signs, 5- only clinical symptoms/signs. The sensitivity of each method was studied to determine their effectiveness as a screening method.    Results: Out of 146 patients who underwent colposcopy, 38 patients had it due to abnormal Pap smears, 37 due to positive VIA, 21 due to abnormality of both these tests, and 50 due to clinical symptoms/signs despite having normal screening tests. The sensitivity for VIA and Pap smear was 73.39% (17.48%-83.31%) and 40.41% (32.47%-48.86%) respectively. Presence of at least one of the three clinical symptoms/signs and a positive VIA found 78.8% of CIN 2+ cases. Presence of at least one of the three clinical symptoms/signs and abnormal Pap smear identified 84.2% of the cases.    Conclusion: To find high-grade CIN, focused attention to the clinical symptoms/signs, even in the presence of normal Pap smear, can increase the sensitivity of Pap smear and VIA. In low resource settings, a simple, highly sensitive method like VIA can be used in addition to or as an alternative to other means.
کلیدواژه‌های انگلیسی مقاله Visual Inspection with Acetic acid, Cervical Intraepithelial Neoplasia, Symptom, Sensitivity, Papanicolaou Test, VIA
نویسندگان مقاله | Nafiseh Faghih
Department of Gyneco-Oncology , School of Mecine, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Maliheh Arab
Department of Gyneco-Oncology , School of Mecine, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Afsaneh Tehranian
Department Obstetrics and Gynecology, School of Mecine, Tehran University of Medical Sciences, Tehran, Iran


| Behnaz Ghavami
Department Obstetrics and Gynecology, School of Mecine, Tehran University of Medical Sciences, Tehran, Iran


| Behnaz Nouri
Department of Gyneco-Oncology , School of Mecine, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Donya Khosravi
Department Obstetrics and Gynecology, School of Mecine, Kermanshah University of Medical Sciences, Kermanshah, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7055-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Gynecology & Obstetrics
نوع مقاله منتشر شده Original Research
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