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Medical Journal of Islamic Republic of Iran، جلد ۳۵، شماره ۱، صفحات ۷۳۷-۷۴۳
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عنوان انگلیسی Predictors of critical COVID-19 in an Iranian population: Age and disabilities play a special role
چکیده انگلیسی مقاله Background: Ever since coronavirus disease 2019 (COVID-19) has emerged as a global public health problem, risk factors for severe disease have been reported in studies from Western countries. However, apart from studies of Chinese origin, few reports are available on COVID-19 severity among the Asian population. This study investigates potential risk factors for development of critical COVID-19 in an Iranian population.    Methods: In this retrospective cohort study, we included all adults with COVID-19 from 2 tertiary centers in Iran who had been diagnosed between February 20 and April 1, 2020, in either inpatient or outpatient settings. "Critical COVID-19" was proposed when a hospitalized patient was scheduled for admission to intensive care unit, assisted by mechanical ventilation, or pronounced dead. We used univariable and multivariable logistic and linear regression models to explore the potential risk factors associated with critical COVID-19, admission to hospital, and length of hospital stay.    Results: Of the 590 recruited patients, 427 (72.4%) were hospitalized, 186 (31.5%) had critical COVID-19, and 107 (18.2%) died. In the multivariable regression analysis, age  >60 years and physical/mental disabilities were associated with critical COVID-19 (odds ratio (OR), 2.33 and 7.03; 95% CI, 1.51-3.60 and 2.88-17.13, respectively); and history of renal, heart, or liver failure was associated with both COVID-19 hospitalization (OR, 4.13; 95% CI 1.91-8.95; p< 0.001) and length of hospital stay (Beta 1.90; 95% CI, 0.76-3.04; p=0.001).    Conclusion: Age >60 years and physical/mental disabilities can predict development of critical COVID-19 in the Iranian population. Also, the presence of renal, heart, or liver failure might predict both COVID-19 hospitalization and length of hospital stay.
کلیدواژه‌های انگلیسی مقاله COVID-19, Prognosis, Risk Factor, Age, Disability, Iran
نویسندگان مقاله | Ali Bidari
Department of Rheumatology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Morteza Hassanzadeh
Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Mahya Naderkhani
Emergency Medicine Management Research Center, Iran University of Medical Sciences, Tehran, Iran


| Milad Gholizadeh Mesgarha
School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Arash Pour Mohammad
Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Alireza Azadeh
School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Hasti Hossein
Physiology Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Elham Zarei
Ali-Asghar Children Hospital, Department of Radiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Mahmoud Khodadost
Department of Epidemiology, School of Public Health, Larestan University of Medical Sciences, Larestan, & Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6676-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده COVID 19
نوع مقاله منتشر شده Original Research
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