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JCR 2016
جستجوی مقالات
دوشنبه 27 بهمن 1404
Medical Journal of Islamic Republic of Iran
، جلد ۳۵، شماره ۱، صفحات ۵۸۶-۵۹۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Risk factors of erosive esophagitis and barrett’s esophagus in patients with reflux symptoms
چکیده انگلیسی مقاله
Background: Gastroesophageal reflux disease (GERD) is a prevalent condition. Erosive esophagitis (EE) and Barrett's esophagus (BE) are the two important complications of GERD. We aimed to study the prevalence of EE and BE in a group of Patients with reflux symptoms who were referred for endoscopy. The relationship between reflux symptoms and endoscopic findings was also examined. Methods: We enrolled 139 consecutive patients with characteristic symptoms of GERD. Demographic and clinical characteristics of the patients including duration and severity of reflux symptoms, were recorded. Endoscopic findings of EE were identified and classified according to the Los Angeles classification, while BE was confirmed by histopathology examination. The Fisher's exact test and the two-sample 𝑡-test were used to test the association of esophageal lesions (BE and/or EE) with the patients' clinical and endoscopic data. Results: Forty seven and 13 patients were found to have EE and BE, respectively. Multivariate analysis showed that older age (p=0.001) and hiatal hernia (p=0.004) was significantly related risk factors for erosive esophagitis and BE. While an increase in BMI (p=0.004) was related to EE, patients with BE were more likely to have severe reflux symptoms than others (p=0.002). Conclusion: In patients with GERD, the presence of hiatal hernia may be strong risk factor for erosive esophagitis and BE, as does older age. For Barrett's esophagus, severe reflux symptoms are more likely.
کلیدواژههای انگلیسی مقاله
Barrett’s esophagus, Reflex esophagitis
نویسندگان مقاله
| Rabah Asreah
Department of Medicine, College of Medicine, University of Baghdad, Baghdad, Iraq
| Ali Abdullhameed
Department of Medicine, Baghdad Teaching Hospital, Baghdad, Iraq
نشانی اینترنتی
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-5957-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده
en
موضوعات مقاله منتشر شده
Gastroenterology
نوع مقاله منتشر شده
Original Research
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