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Medical Journal of Islamic Republic of Iran، جلد ۳۵، شماره ۱، صفحات ۴۲۹-۴۳۴
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عنوان انگلیسی Hearing status in patients with overdose of illicit drugs
چکیده انگلیسی مقاله Background: The overdose of illicit drugs is not always fatal but can lead to various complications. One of the unusual medical complications is a sensorineural hearing loss (SNHL). There are multiple case reports about this subject. Considering the importance of hearing loss on quality of life, we investigated hearing status in patients with overdose of illicit drugs.    Methods: This cross-sectional study was performed in Loghman Hakim hospital in Shahid Beheshti University of Medical Sciences, Tehran, Iran, in 2016-2017. The hearing status of 95 patients with illicit drugs overdose and 44 healthy individuals were assessed using standard pure tone audiometry and distortion product otoacoustic emissions. The patient group was categorized based on hearing status and compared based on some variables. We applied 2 independent t tests, Mann-Whitney, Chi-square, and binary logistic regression tests. All analyses were conducted in Stata 12 (STATA Corp, USA) and significance level was set at less than 0.05.    Results: We found higher percentage frequency of SNHL in the patient group than the control group (15.8% vs 2.3%; p=0.021). The frequency of hearing loss was 21.7% in opioid users, 5.3% in stimulant users, and 6.3% in concomitant use of both. There was a significant relationship between SNHL and overdose of illicit drugs (aOR = 14.48, 95% CI = 1.53-136.44; p=0.019) with adjusting age, sex, and smoking.    Conclusion: Illicit drugs overdose can potentially affect the hearing system. Opioid drugs, especially methadone and tramadol, have been found to affect the hearing system. Therefore, it is important to conduct longitudinal studies to demonstrate the role of opioid drugs on the hearing system.
کلیدواژه‌های انگلیسی مقاله Hearing Loss, Illicit Drugs, Inner Ear
نویسندگان مقاله | Farhad Mokhtarinejad
Hearing Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Ali Asghar Peyvandi
1. Hearing Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Shahin Shadnia
Toxicology Research Center, & Loghman-Hakim Hospital Poison Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Hassan Peyvandi
Hearing Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Manijeh Rezvani
Loghman-Hakim Hospital Poison Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Shahrokh Khoshsirat
Hearing Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mahbobeh Oroei
Hearing Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-4655-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Audiology
نوع مقاله منتشر شده Original Research
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