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Medical Journal of Islamic Republic of Iran، جلد ۳۵، شماره ۱، صفحات ۵۰-۵۹
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عنوان انگلیسی Clinical features of 50 cases of 2019 novel coronavirus in Bandar Abbas, Iran
چکیده انگلیسی مقاله Background: There is sparse information to describe the clinical features and outcomes of patients infected with coronavirus disease 2019 (COVID-19).     Methods: In a single-center retrospective observational study, 50 patients infected with COVID-19 were studied. Epidemiological, demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed. Outcomes of critically ill patients and noncritically ill patients were compared.     Results: The mean age of the patients was 48.8 years, with male predominance. Dry cough, fever, and dyspnea were the most complaining symptoms on admission. Chronic medical illnesses before admission were present in 56% of the patients. The most common laboratory abnormalities were lymphopenia, neutrophilia, thrombocytopenia, increased aspartate aminotransferase, high serum creatinine level, elevated lactate dehydrogenase, and increasing ESR and CRP levels. Bilateral mixed ground-glass opacity and consolidation were observed in chest CT scan of most patients. Some patients required supplemental oxygen and some needed invasive mechanical ventilation. Blood oxygen saturation was different between survivors and nonsurvivors. 10% of patients died, of whom 60% were men. 40% of dead cases had chronic medical illnesses; 60% underwent invasive mechanical ventilation.    Conclusion: Among the patients diagnosed with COVID-19 infection, the frequent clinical presentation was with a wide range of signs and symptoms. The laboratory changes suggest that COVID-19 infection may be related to cellular immune deficiency, myocardial, hepatic, and kidney injury. Additional research is needed to elucidate COVID-19 pathogenesis.  
کلیدواژه‌های انگلیسی مقاله SARS-CoV-2, Coronavirus disease 2019, COVID-19, Clinical features, Laboratory, Chest CT scan, Outcomes
نویسندگان مقاله | Hashem Jarineshin
Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Fateme Saljoughi
Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Hamideh Estabraghnia Babaki
Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Mehdi Hassaniazad
Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Masoumeh kheirandish
Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Amin Ghanbarnejad
Social Determinants in Health Promotion Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Shahla Sohrabipour
Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6054-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Disease
نوع مقاله منتشر شده Original Research
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