این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Nuclear Medicine، جلد ۲۹، شماره ۱، صفحات ۱۵-۲۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Diagnostic performance of 18F-FDG PET-CT in patients presenting with secondary neck nodes from an unknown primary
چکیده انگلیسی مقاله Introduction: Clinical examination and even anatomical imaging may fail to identify primary site of malignancy in patients presenting with cervical nodal metastasis. 18F-Fluorodeoxyglucose Positron Emission Computed Tomography (18F-FDG PET-CT) is known to overcome the limitations of anatomic imaging. Methods: Sixty-three (63) patients (male:female=55:8, age range=32-83 years, mean age=61.14 ±12.6 years) with one or more metastatic neck node (s) from occult primary underwent 18F-FDG PET-CT. Nodal cytological/biopsy findings, IHC of cervical nodal biopsy (whenever available), scan findings, subsequent biopsy findings (PET guided/ directed) of suggested occult primaries were correlated. Subsequent detection of any primary malignancy in whom 18F-FDG PET-CT failed to localize a primary was also documented. Results: Malignancy was confirmed in eighteen (18) out of those twenty-four (24) patients in whom site of possible occult primary malignancy was suggested out of total sixty-three (63) patients. In five (5) patients out of remaining thirty-nine (39) patients, a site of primary malignancy was detected or a site of primary malignancy was considered based on IHC subsequently. The detection rate of occult primary, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and false positivity rate was calculated to be 28.5%, 78.2%, 85%, 75%, 87.1% and 15% respectively. 18F-FDG PET-CT also detected other lymph nodal and organ metastases in 46% and 23.8% patients respectively. Conclusion: 18F-FDG PET-CT is a useful modality for detecting unknown primary and other nodal /distant metastases in patients presenting with neck nodal metastases.
کلیدواژه‌های انگلیسی مقاله Metastatic neck nodes, Carcinoma of unknown primary, 18F-FDG PET-CT
نویسندگان مقاله Manjit Sarma |
Department of Nuclear Medicine and Molecular Imaging, Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, India

Subramanyam Padma |
Department of Nuclear Medicine and Molecular Imaging, Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, India

Palaniswamy Shanmuga Sundaram |
Department of Nuclear Medicine and Molecular Imaging, Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, India

نشانی اینترنتی http://irjnm.tums.ac.ir/article_39903_0e695104441439fbb92eb190123e84df.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات