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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۵، شماره ۲، صفحات ۱۳۲-۱۳۴
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عنوان انگلیسی Massive Splenomegaly: A Rare Presentation of Megaloblastic Anemia
چکیده انگلیسی مقاله Megaloblastic anemia is a common disorder with various manifestations. Of the many causes, cobalamin or folate deficiency can eventuate into megaloblastic anemia. It can lead to pancytopenia and mild to moderate splenomegaly, but massive splenomegaly rarely seen in this situation. We describe a 39-year-old woman with marked enlargement of the spleen and pancytopenia that was found to have megaloblastic anemia. The splenomegaly and blood count resolved 4 months after initiation of vitamin B12 therapy. It is important to know massive splenomegaly may occur in megaloblastic anemia, and although it is rare, bur can reversible with early treatment.
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نویسندگان مقاله | Tahereh Gholipour
Department of Clinical Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran


| Alireza Sadeghi
Department of Internal Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran


| Padideh Oghab
Department of Oncology and Hematology, Isfahan University of Medical Sciences, Isfahan, Iran


| Pegah Farrokhi
Department of Clinical Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran


| Azadeh Moghaddas
Department of Clinical Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran
نشانی اینترنتی https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1211
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